Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19106731 | 0.82 | PIK3CD (0.47) | PIK3CDLMNABRD4BRD2CHRM2 | |
| SCHEMBL25988587 | 0.80 | BRD4 (0.39) | PIK3CDLMNABRD4BRD2CHRM2 | |
| SCHEMBL19918791 | 0.80 | BRD4 (0.39) | PIK3CDLMNABRD4BRD2CHRM2 | |
| SCHEMBL6608794 | 0.79 | BRD4 (0.38) | PIK3CDLMNABRD4BRD2CHRM2 | |
| SCHEMBL19918839 | 0.77 | BRD4 (0.36) | PIK3CDLMNABRD4BRD2CA12 | |
| SCHEMBL21104914 | 0.76 | PIK3CD (0.41) | PIK3CDLMNABRD4BRD2CHRM2 | |
| SCHEMBL11028833 | 0.76 | ALOX5 (0.38) | PIK3CDLMNABRD4BRD2CCR2 | |
| SCHEMBL10093754 | 0.76 | BRD4 (0.41) | PIK3CDLMNAL3MBTL1BRD4BRD2 | |
| SCHEMBL18799321 | 0.75 | BRD4 (0.33) | PIK3CDLMNAL3MBTL1BRD4BRD2 | |
| SCHEMBL24409413 | 0.75 | ALOX5 (0.41) | PIK3CDLMNABRD4BRD2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053446-A2 | PREGABALIN INTERMEDIATES AND PROCESS FOR PREPARING THEM AND PREGABALIN | CHEMO IBÉRICA, S.A. (ES) | 2009-04-30 | — | — | WO | claimed |
| WO-2009053446-A2 | PREGABALIN INTERMEDIATES AND PROCESS FOR PREPARING THEM AND PREGABALIN | CHEMO IBÉRICA, S.A. (ES) | 2009-04-30 | — | — | WO | disclosed |