Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.43 |
| ▸ | PGR | P06401 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175488 | 0.92 | NR3C1 (0.66) | NR3C1NR3C2PGR | |
| SCHEMBL3974262 | 0.87 | NR3C1 (0.68) | NR3C1NR3C2PGR | |
| SCHEMBL304016 | 0.86 | NR3C1 (0.65) | NR3C1NR3C2PGR | |
| SCHEMBL1776759 | 0.86 | NR3C1 (0.74) | NR3C1NR3C2PGR | |
| SCHEMBL1775960 | 0.86 | NR3C1 (0.74) | NR3C1NR3C2PGR | |
| SCHEMBL1776758 | 0.86 | NR3C1 (0.74) | NR3C1NR3C2PGR | |
| SCHEMBL304100 | 0.85 | NR3C1 (0.67) | NR3C1NR3C2PGR | |
| SCHEMBL304461 | 0.84 | NR3C1 (0.63) | NR3C1NR3C2PGR | |
| SCHEMBL304274 | 0.84 | NR3C1 (0.63) | NR3C1NR3C2PGR | |
| SCHEMBL13884914 | 0.84 | NR3C1 (0.65) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050220-A1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |