SCHEMBL3974097

SCHEMBL3974097

CCN(CC)CCNS(=O)(=O)c1cc[c]cc1

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.69
ALDH1A1 P00352 1/20 0.59
MAPK1 P28482 1/20 0.59
GFER P55789 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.56
USP2 O75604 1/20 0.54
KMT2A Q03164 1/20 0.53
NEK1 Q96PY6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6295282 0.91 USP2 (0.66) SIGMAR1ALDH1A1MAPK1GFERSMN1; SMN2
SCHEMBL7011356 0.89 USP2 (0.60) SIGMAR1ALDH1A1MAPK1GFERSMN1; SMN2
SCHEMBL7506700 0.84 SIGMAR1 (0.50) SIGMAR1ALDH1A1MAPK1GFERSMN1; SMN2
SCHEMBL3971066 0.83 TSHR (0.66) SIGMAR1ALDH1A1KMT2ANEK1
SCHEMBL3712996 0.83 SIGMAR1 (0.73) SIGMAR1ALDH1A1MAPK1GFERSMN1; SMN2
SCHEMBL6034681 0.82 SIGMAR1 (1.00) SIGMAR1ALDH1A1MAPK1GFERSMN1; SMN2
SCHEMBL7014515 0.81 CA12 (0.62) SIGMAR1ALDH1A1SMN1; SMN2KMT2A
SCHEMBL1674212 0.81 SIGMAR1 (0.74) SIGMAR1ALDH1A1MAPK1GFERSMN1; SMN2
SCHEMBL3324949 0.81 SIGMAR1 (0.74) SIGMAR1ALDH1A1MAPK1GFERSMN1; SMN2
SCHEMBL9510691 0.81 SIGMAR1 (1.00) SIGMAR1ALDH1A1MAPK1GFERSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7495040-B2 Actinic ray curable composition, image forming method using the same and ink-jet recording apparatus using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-02-24 US disclosed
US-20080012918-A1 Actinic Radiation Curable Ink-Jet Ink, And Image Forming Method And Ink-Jet Recording Apparatus Using The Same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-01-17 US disclosed
US-20050196697-A1 Actinic ray curable composition, image forming method using the same and ink-jet recording apparatus using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-09-08 US disclosed
US-20050165123-A1 Actinic ray curable composition, image forming method using the same and ink-jet recording apparatus using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-07-28 US disclosed
US-6855719-B1 Imidazo[1,2-A]pyridine and pyrazolo[2,3-A]pyridine derivatives ASTRAZENECA AB (SE) 2005-02-15 US disclosed
CN-1174981-C Imidazo [1, 2-A ] pyridine and pyrazolo [2, 3-A ] pyridine derivatives 2004-11-10 CN disclosed
EP-1214318-B1 IMIDAZO[1,2-A]PYRIDINE AND PYRAZOLO[2,3-A]PYRIDINE DERIVATIVES ASTRAZENECA AB (SE) 2003-10-08 EP disclosed
CN-1370163-A Imidazo [1,2-A] pyridine and pyrazolo [2,3-a] pyridine derivatives ASTRAZENECA AB (SE) 2002-09-18 CN disclosed
EP-1214318-A1 IMIDAZO[1,2-A]PYRIDINE AND PYRAZOLO[2,3-A]PYRIDINE DERIVATIVES AstraZeneca AB (SE) 2002-06-19 EP disclosed
WO-2001014375-A1 IMIDAZO[1,2-A]PYRIDINE AND PYRAZOLO[2,3-A]PYRIDINE DERIVATIVES ASTRAZENECA AB (SE) 2001-03-01 WO disclosed