Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.42 |
| ▸ | PPARG | P37231 | 18/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1929958 | 0.96 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL3972003 | 0.90 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL3976365 | 0.90 | PPARA (0.39) | PPARAPPARGPPARD | |
| SCHEMBL6265093 | 0.90 | ALDH1A1 (0.44) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL5181030 | 0.90 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL5180785 | 0.88 | PPARA (0.40) | PPARAPPARGPPARD | |
| SCHEMBL5178764 | 0.88 | ALDH1A1 (0.44) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL5181686 | 0.88 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL1929331 | 0.87 | PPARA (0.43) | PPARAPPARGPPARDSLC16A3SLC16A1 | |
| SCHEMBL1929335 | 0.87 | PPARA (0.43) | PPARAPPARGPPARDSLC16A3SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778655-B1 | 2 - { - 3 2 - (PHENYL)-OXAZOL-4-YLMETHOXYL-CYCLOHEXYLMETHOXY}-PROPIONIC ACID DERIVATIVES USED AS PPAR LIGANDS (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS) FOR THE TREATMENT OF HYPERLIPIDAEMIE AND DIABETES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-05-06 | — | — | EP | disclosed |