Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13885267 | 0.91 | NR3C1 (0.61) | NR3C1 | |
| SCHEMBL3974294 | 0.90 | NR3C1 (0.59) | NR3C1 | |
| SCHEMBL13884005 | 0.90 | NR3C1 (0.56) | NR3C1 | |
| SCHEMBL3980656 | 0.89 | NR3C1 (0.64) | NR3C1 | |
| SCHEMBL13884921 | 0.85 | NR3C1 (0.65) | NR3C1 | |
| SCHEMBL13884786 | 0.84 | NR3C1 (0.64) | NR3C1 | |
| SCHEMBL3973377 | 0.84 | NR3C1 (0.59) | NR3C1 | |
| SCHEMBL3973979 | 0.81 | NR3C1 (0.62) | NR3C1 | |
| SCHEMBL1775338 | 0.81 | NR3C1 (0.61) | NR3C1 | |
| SCHEMBL13883928 | 0.81 | NR3C1 (0.54) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050221-A1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | WO | claimed |
| WO-2009050221-A1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009050221-A1 | INDAZOLES AS GLUCOCORTICOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |