SCHEMBL3974479

SCHEMBL3974479

O=P(O)(O)C(Cl)(c1ccc(Cl)cc1)P(=O)(O)O.O=P(O)(O)C(Cl)(c1ccccc1)P(=O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.48
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
HIF1A Q16665 1/20 0.47
PGK1 P00558 3/20 0.46
PGK2 P07205 3/20 0.46
PTPN5 P54829 3/20 0.43
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP1A2 P05177 1/20 0.41
MIF P14174 1/20 0.40
KIF11 P52732 2/20 0.40
PTGS2 P35354 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4095380 0.92 TSHR (0.54) TSHRMAPK1HIF1APGK1PGK2
SCHEMBL4099292 0.90 PTPN1 (0.58) PTPN1TSHRPGK1PGK2PTPN5
Water SCHEMBL5162861 0.88 PTPN1 (0.56) PTPN1TSHRPGK1PGK2PTPN5
SCHEMBL9447756 0.77 TSHR (0.50) TSHRMAPK1HIF1ALMNAHTT
SCHEMBL3903209 0.77 TSHR (0.50) TSHRMAPK1HIF1ALMNACYP1A2
SCHEMBL11773996 0.75 PGK1 (0.57) TSHRMAPK1HIF1APGK1PGK2
SCHEMBL8157070 0.74 TSHR (0.53) TSHRMAPK1HIF1ALMNACYP1A2
SCHEMBL3949150 0.74 TSHR (0.53) TSHRMAPK1HIF1ALMNACYP1A2
Chlorobenzene SCHEMBL27645436 0.74 TSHR (0.61) PTPN1TSHRCYP1A2PTGS2
SCHEMBL14029153 0.74 TSHR (0.46) TSHRPGK1PGK2PTPN5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2057303-A1 CHROMIUM-FREE, THERMALLY CURABLE CORROSION PROTECTION COMPOSITION Henkel AG & Co. KGaA (DE) 2009-05-13 EP disclosed
WO-2008022819-A1 CHROMIUM-FREE, THERMALLY CURABLE CORROSION PROTECTION COMPOSITION HENKEL AG & CO. KGAA (DE) 2008-02-28 WO disclosed