Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974663 | 0.88 | DPP4 (0.41) | DPP4CHRM1KCNH2CHRM2CHRM3 | |
| SCHEMBL3971380 | 0.82 | DPP4 (0.40) | DPP4CHRM1KCNH2 | |
| SCHEMBL3971512 | 0.81 | DPP4 (0.39) | DPP4CHRM1KCNH2CHRM2CHRM3 | |
| SCHEMBL3973726 | 0.81 | DPP4 (0.39) | DPP4 | |
| SCHEMBL3975266 | 0.81 | DPP4 (0.39) | DPP4KCNH2 | |
| SCHEMBL3965788 | 0.80 | DPP4 (0.36) | DPP4 | |
| SCHEMBL3971268 | 0.80 | DPP4 (0.38) | DPP4KCNH2 | |
| SCHEMBL3971303 | 0.78 | DPP4 (0.37) | DPP4KCNH2 | |
| SCHEMBL1071796 | 0.78 | DPP4 (0.37) | DPP4 | |
| SCHEMBL3973460 | 0.77 | TP53 (0.38) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569574-B2 | Purine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2009-08-04 | — | — | US | disclosed |
| US-20040122228-A1 | New purine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122228-A1 | New purine derivatives, the preparation thereof and their use as pharmaceutical compositions | DPP4, DPP7, DPP3 | DPP4 1/4885CHRM1 1289/4885KCNH2 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.