Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3981991 | 0.89 | GCGR (0.69) | GCGRMAPT | |
| SCHEMBL12951737 | 0.89 | GCGR (0.61) | GCGRKMT2AAURKBMAPT | |
| SCHEMBL12951665 | 0.87 | GCGR (0.73) | GCGRKMT2AAURKBMAPT | |
| SCHEMBL178543 | 0.87 | GCGR (0.70) | GCGRAURKB | |
| SCHEMBL3975108 | 0.87 | GCGR (0.73) | GCGRKMT2AAURKBPOLBMAPT | |
| Hydrochloric Acid SCHEMBL141155 | 0.86 | GCGR (0.69) | GCGRAURKB | |
| SCHEMBL3976571 | 0.85 | GCGR (0.69) | GCGRKMT2AAURKB | |
| SCHEMBL3978407 | 0.85 | GCGR (0.81) | GCGRKMT2AAURKBMAPT | |
| SCHEMBL3978688 | 0.83 | GCGR (0.68) | GCGRKMT2APOLBMAPT | |
| SCHEMBL3979045 | 0.83 | GCGR (0.73) | GCGRAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514452-B2 | 2-furancarboxylic acid hydrazides and pharmaceutical compositions containing the same | DAINIPPON PHARMACEUTICAL CO., LTD (JP) | 2009-04-07 | — | — | US | disclosed |
| US-20050171196-A1 | 2-Furancarboxylic acid hydrazides and pharmaceutical compositions containing the same | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-08-04 | — | — | US | disclosed |
| EP-1489077-A1 | 2-FURANCARBOXYLIC ACID HYDRAZIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171196-A1 | 2-Furancarboxylic acid hydrazides and pharmaceutical compositions containing the same | GLP1R, GCGR, GPR119 | GCGR 2/4885KMT2A 3459/4885AURKB 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.