Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 2/20 | 0.61 |
| ▸ | FLT3 | P36888 | 1/20 | 0.60 |
| ▸ | MELK | Q14680 | 3/20 | 0.53 |
| ▸ | BTK | Q06187 | 2/20 | 0.52 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | FER | P16591 | 1/20 | 0.52 |
| ▸ | MATK | P42679 | 1/20 | 0.52 |
| ▸ | BLK | P51451 | 1/20 | 0.52 |
| ▸ | BMX | P51813 | 1/20 | 0.52 |
| ▸ | TEK | Q02763 | 1/20 | 0.52 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.52 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.52 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971090 | 0.89 | CCR4 (0.62) | CCR4FLT3MELKBTKERBB4 | |
| SCHEMBL3975275 | 0.86 | CCR4 (0.63) | CCR4FLT3BTKERBB4USP2 | |
| SCHEMBL3971151 | 0.85 | CCR4 (0.68) | CCR4BTKERBB4USP2CYP2D6 | |
| SCHEMBL6673288 | 0.85 | CCR4 (0.68) | CCR4BTKERBB4USP2CYP2D6 | |
| SCHEMBL3974901 | 0.84 | SLC2A1 (0.72) | FLT3SLC2A1MEN1KMT2APOLB | |
| SCHEMBL3973975 | 0.83 | CCR4 (0.60) | CCR4MELKBTKERBB4USP2 | |
| Hydrochloric Acid SCHEMBL5260533 | 0.82 | CCR4 (0.58) | CCR4FLT3MELKBTKERBB4 | |
| SCHEMBL3980413 | 0.81 | SLC2A1 (0.62) | FLT3HSD17B10SLC2A1KDM4EMEN1 | |
| SCHEMBL31500268 | 0.79 | USP2 (0.76) | FLT3USP2CYP2D6TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL31500254 | 0.78 | USP2 (0.76) | FLT3USP2CYP2D6TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547702-B2 | 4-amino-quinazolines | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-20060019974-A1 | Glycoprotein antagonist; anticholesterol agents; cardiovascular disorders; strokes; antiischemic agents | ORTHO-MCNEIL PHARMACEUTICALS, INC. | 2006-01-26 | — | — | US | disclosed |
| WO-2004030672-A1 | USE OF 4 AMINO-QUINAZOLINES AS ANTI CANCER AGENTS | MERCK PATENT GMBH (DE) | 2004-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019974-A1 | Glycoprotein antagonist; anticholesterol agents; cardiovascular disorders; strokes; antiischemic agents | SERPINA3, APOL1, MGAT3 | CCR4 3890/4885FLT3 1822/4885MELK 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.