Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977167 | 0.89 | MAPKAPK2 (0.50) | MAPKAPK2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3975984 | 0.79 | NAMPT (0.57) | MAPKAPK2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3710489 | 0.78 | HDAC1 (0.49) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL847829 | 0.76 | HDAC1 (0.48) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL6237639 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL19997538 | 0.73 | ALDH1A1 (0.55) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL3976381 | 0.73 | ALDH1A1 (0.58) | ALDH1A1HPGDKMT2ALMNAMAPT | |
| SCHEMBL19851224 | 0.72 | ALDH1A1 (0.62) | ALDH1A1HPGDMEN1KMT2ALMNA | |
| SCHEMBL16193026 | 0.72 | PLAU (0.59) | MAPKAPK2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16193025 | 0.71 | NAMPT (0.60) | MAPKAPK2ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053448-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2009-04-30 | — | — | WO | disclosed |