Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL3377726 | 1.00 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL430711 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL4394984 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL4727295 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL41916 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL7921325 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL76402 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29355915 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1716944 | 0.95 | CA4 (0.76) | CA4 | |
| Citric Acid SCHEMBL1939442 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121583646-A | Composite conductive material and preparation method and application thereof | 广东电网有限责任公司惠州供电局 | 2026-02-27 | — | — | CN | claimed |
| CN-119929874-A | Tin sulfide/bismuth sulfide composite material and preparation method and application thereof | 中国科学院山西煤炭化学研究所 | 2025-05-06 | — | — | CN | claimed |
| CN-115747845-B | Bismuth-doped zinc-based metal organic framework material and preparation method and application thereof | 华南理工大学 | 2025-04-22 | — | — | CN | claimed |
| CN-119318980-A | Hollow carbon sphere epitaxial growth Bi4O5Br2Preparation method of nanosheet confinement reactor and CO thereof2Hydrogenation applications | 江苏大学 | 2025-01-17 | — | — | CN | claimed |
| CN-117050725-B | Radiation blocking and sterilizing dual-function complexing agent and preparation method and application thereof | 山东恒一高新技术产业有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119198861-A | Preparation of nitrogen-sulfur-boron doped carbon/bismuth composite material modified electrode and application of electrode in electrochemical detection of heavy metal ions | 兰州大学 | 2024-12-27 | — | — | CN | claimed |
| CN-118698567-B | Halogen perovskite-based heterojunction composite material and synthetic method and application thereof | 中国市政工程西北设计研究院有限公司 | 2024-12-20 | — | — | CN | claimed |
| CN-119133478-A | Application of carbon nanofiber electrode material with high hydrogen evolution overpotential and high activity in vanadium battery | 辽宁大学 | 2024-12-13 | — | — | CN | claimed |
| CN-119029223-A | Preparation method of anode catalyst of alkaline system fuel cell | 南通大学 | 2024-11-26 | — | — | CN | claimed |
| CN-119016071-A | Nano fluorine doped bismuth titanate and preparation method thereof | 阜阳师范大学 | 2024-11-26 | — | — | CN | claimed |
| EP-0910388-B1 | PHARMACEUTICAL PREPARATION FOR THE TREATMENT OF GASTRITIS, REFLUX OESOPHAGITIS, DUODENITIS, DYSPEPSIA AND ULCER DISEASE | KROTKIEWSKI MARCIN (SE) | 2002-09-18 | — | — | EP | claimed |
| EP-0910388-A1 | PHARMACEUTICAL PREPARATION FOR THE TREATMENT OF GASTRITIS, REFLUX OESOPHAGITIS, DUODENITIS, DYSPEPSIA AND ULCER DISEASE | Krotkiewski, Marcin (SE) | 1999-04-28 | — | — | EP | claimed |
| US-5733163-A | Shadow mask including electron reflection layer and method for manufacturing the same | SAMSUNG DISPLAY DEVICES CO., LTD. (KR) | 1998-03-31 | — | — | US | claimed |
| WO-1997036599-A1 | PHARMACEUTICAL PREPARATION FOR THE TREATMENT OF GASTRITIS, REFLUX OESOPHAGITIS, DUODENITIS, DYSPEPSIA AND ULCER DISEASE | KROTKIEWSKI MARCIN (SE) | 1997-10-09 | — | — | WO | claimed |
| US-5064857-A | LIQUID BISMUTH CONTAINING MEDICINAL PRODUCT, PROCESS FOR PRODUCING IT AND ITS USE | R. PFLEGER CHEMISCHE FABRIK GMBH (DE) | 1991-11-12 | — | — | US | claimed |
| US-5055173-A | Gold cyanide derivatives, bismuth compounds and phosphonic acid compounds | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | claimed |
| US-4953560-A | Apparatus, method, and test kit for diagnosis of vaginal yeast infections | SAMUELS BERNARD (US) | 1990-09-04 | — | — | US | claimed |
| US-4670245-A | ULCERS | VASQUEZ TONY E | 1987-06-02 | — | — | US | claimed |
| US-4153685-A | AS AN AMMONIUM CARBOXYLATE DOUBLE SALT, WITH A PROTEIN; NONDIALYSABLE ANTIULCER AGENTS | SCHERING CORPORATION (US) | 1979-05-08 | — | — | US | claimed |
| US-4093649-A | Liquid phase oxidation of unsaturated aldehydes to carboxylic acids with a bismuth catalyst | ATLANTIC RICHFIELD COMPANY (US) | 1978-06-06 | — | — | US | claimed |