Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254213 | 0.81 | CHRM3 (0.66) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2251112 | 0.72 | CHRM3 (0.67) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4762415 | 0.70 | MEN1 (0.41) | CHRM3CHRM2CHRM1 | |
| Bromide SCHEMBL4631513 | 0.69 | CHRM3 (0.85) | CHRM3CHRM2CHRM1 | |
| SCHEMBL15210058 | 0.67 | CHRM3 (0.71) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4910595 | 0.63 | CHRM3 (0.74) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1009919 | 0.63 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1009920 | 0.63 | CHRM3 (1.00) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4905800 | 0.61 | CHRM3 (0.74) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4168576 | 0.61 | CHRM3 (0.89) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937230-A4 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-08-26 | — | — | EP | disclosed |
| EP-1937230-A2 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007016650-A2 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |