Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157584 | 0.84 | CHRM3 (0.56) | MEN1KMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL5428922 | 0.84 | CHRM3 (0.56) | MEN1KMT2ACHRM3CHRM2CHRM1 | |
| SCHEMBL4914195 | 0.80 | CHRM3 (0.63) | CHRM3CHRM2CHRM1 | |
| Bromide SCHEMBL4665143 | 0.72 | CHRM3 (0.68) | CHRM3CHRM2CHRM1 | |
| Bromide SCHEMBL4665139 | 0.72 | CHRM3 (0.68) | CHRM3CHRM2CHRM1 | |
| SCHEMBL3975188 | 0.70 | CHRM3 (0.51) | CHRM3CHRM2CHRM1 | |
| Iodide SCHEMBL3824722 | 0.69 | CHRM3 (0.67) | CHRM3CHRM2CHRM1 | |
| Iodide SCHEMBL3824719 | 0.69 | CHRM3 (0.67) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2251112 | 0.69 | CHRM3 (0.67) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5438579 | 0.69 | CHRM3 (0.63) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781103-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-05-14 | — | — | EP | disclosed |
| EP-1781103-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006017767-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |