Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918627 | 0.90 | CYP3A4 (0.65) | CYP3A4TRPA1TSHRTDP1MAPK1 | |
| SCHEMBL29874510 | 0.90 | CYP3A4 (0.65) | CYP3A4TRPA1TSHRTDP1MAPK1 | |
| SCHEMBL29384050 | 0.90 | CYP3A4 (0.65) | CYP3A4TRPA1TSHRTDP1MAPK1 | |
| SCHEMBL9813322 | 0.90 | CYP3A4 (0.61) | CYP3A4TRPA1TSHRTDP1MAPK1 | |
| SCHEMBL24999152 | 0.89 | CYP3A4 (0.61) | CYP3A4TRPA1TSHRTDP1MAPK1 | |
| SCHEMBL9813344 | 0.87 | CYP3A4 (0.57) | CYP3A4TRPA1TSHRTDP1MAPK1 | |
| SCHEMBL29708073 | 0.87 | CYP3A4 (0.51) | CYP3A4TRPA1TSHRTDP1MAPK1 | |
| SCHEMBL483400 | 0.85 | CYP3A4 (0.58) | CYP3A4TRPA1TSHRTDP1MAPK1 | |
| SCHEMBL26469 | 0.85 | CYP3A4 (0.56) | CYP3A4TRPA1TSHRTDP1MAPK1 | |
| SCHEMBL5500495 | 0.81 | CYP3A4 (0.53) | CYP3A4TRPA1TSHRTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538163-B2 | Modification of thermoplastic polymers | MEDTRONIC, INC. (US) | 2009-05-26 | — | — | US | disclosed |
| EP-1877461-B1 | MODIFICATION OF THERMOPLASTIC POLYMERS | MEDTRONIC INC (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1877461-A2 | MODIFICATION OF THERMOPLASTIC POLYMERS | Medtronic, Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| US-20060223955-A1 | Modification of thermoplastic polymers | MEDTRONIC, INC. | 2006-10-05 | — | — | US | disclosed |
| WO-2006102603-A2 | MODIFICATION OF THERMOPLASTIC POLYMERS | MEDTRONIC, INC. (US) | 2006-09-28 | — | — | WO | disclosed |