Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.59 |
| ▸ | PPARA | Q07869 | 16/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974615 | 0.94 | PPARG (0.68) | PPARGPPARAHDAC1PGR | |
| SCHEMBL5983770 | 0.84 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL3970004 | 0.83 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL3973228 | 0.81 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL3978911 | 0.78 | KDM4E (0.52) | PPARGPPARAHDAC1 | |
| SCHEMBL3972386 | 0.78 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL3980861 | 0.78 | PPARG (0.56) | PPARGPPARAHDAC1 | |
| SCHEMBL5983805 | 0.77 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL3974851 | 0.77 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL3978857 | 0.77 | PPARG (0.53) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | claimed |
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | disclosed |
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20060020003-A1 | Biphenyloxy-acids | WYETH (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020003-A1 | Biphenyloxy-acids | AHR, ARNT, NR1H4 | PPARG 88/4885PPARA 30/4885HDAC1 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.