Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975674 | 0.86 | HTT (0.47) | HTTSMN1; SMN2RAB9AALDH1A1GAA | |
| SCHEMBL18184378 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL28072114 | 0.72 | ALDH1A1 (0.47) | HTTSMN1; SMN2ALDH1A1RECQLPOLB | |
| SCHEMBL5508609 | 0.70 | — | — | |
| SCHEMBL1112185 | 0.70 | — | — | |
| SCHEMBL20993528 | 0.69 | ALDH1A1 (0.44) | HTTSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL19919837 | 0.69 | ALDH1A1 (0.44) | HTTSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL7299085 | 0.68 | ALDH1A1 (0.43) | HTTSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL20368086 | 0.67 | ALDH1A1 (0.42) | HTTSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL7355004 | 0.67 | ALDH1A1 (0.42) | HTTSMN1; SMN2ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057115-A1 | 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008024746-A1 | 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES | ARRAY BIOPHARMA, INC. (US) | 2008-02-28 | — | — | WO | disclosed |