Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 7/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044893 | 0.91 | NPSR1 (0.61) | NPSR1KMT2AMEN1TSHRNPC1 | |
| SCHEMBL7153902 | 0.91 | ESR1 (0.47) | ESR1ESR2KMT2AMEN1TSHR | |
| SCHEMBL741752 | 0.89 | NPSR1 (0.64) | NPSR1KMT2AMEN1TSHRNPC1 | |
| Hydrochloric Acid SCHEMBL8550497 | 0.87 | NPSR1 (0.61) | NPSR1KMT2AMEN1TSHRNPC1 | |
| SCHEMBL1471487 | 0.85 | NPSR1 (0.54) | NPSR1KMT2AMEN1TSHRNPC1 | |
| SCHEMBL5540103 | 0.83 | NPSR1 (0.52) | NPSR1KMT2AMEN1TSHRNPC1 | |
| SCHEMBL197621 | 0.82 | NPSR1 (0.56) | NPSR1KMT2AMEN1TSHRNPC1 | |
| SCHEMBL8009586 | 0.82 | NPSR1 (0.50) | NPSR1KMT2AMEN1TSHRNPC1 | |
| SCHEMBL4849374 | 0.82 | NPSR1 (0.50) | NPSR1KMT2AMEN1TSHRNPC1 | |
| SCHEMBL5605036 | 0.82 | NPC1 (0.54) | NPSR1KMT2AMEN1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| EP-1271143-B1 | Test strip having a porous filter layer | ARKRAY INC (JP) | 2009-05-06 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-7201871-B2 | Specimen having capability of separating solid component | ARKRAY INC. (JP) | 2007-04-10 | — | — | US | disclosed |
| US-7189576-B2 | Method for measuring substance and testing piece | ARKRAY INC. (JP) | 2007-03-13 | — | — | US | disclosed |
| US-7153696-B2 | Method for measuring substance and testing piece | ARKRAY INC. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-7098038-B2 | Method for measuring substance and testing piece | ARKRAY INC. (JP) | 2006-08-29 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-0860695-B1 | Method for measuring an analyte and corresponding device | ARKRAY INC (JP) | 2006-01-04 | — | — | EP | disclosed |
| US-20030180183-A1 | Method for measuring substance and testing piece | FUKUOKA TAKAO (JP) | 2003-09-25 | — | — | US | disclosed |
| US-20030175985-A1 | Method for measuring substance and testing piece | FUKUOKA TAKAO (JP) | 2003-09-18 | — | — | US | disclosed |
| US-20030175984-A1 | Method for measuring substance and testing piece | FUKUOKA TAKAO (JP) | 2003-09-18 | — | — | US | disclosed |
| US-20030166295-A1 | Method for measuring substance and testing piece | FUKUOKA TAKAO (JP) | 2003-09-04 | — | — | US | disclosed |
| CN-1429339-A | Test piece with capability of separating solid | ARKRAY INC (JP) | 2003-07-09 | — | — | CN | disclosed |
| US-20030044316-A1 | Specimen having capability of separating solid component | ARKRAY INC. (JP) | 2003-03-06 | — | — | US | disclosed |
| EP-1271143-A1 | SPECIMEN HAVING CAPABILITY OF SEPARATING SOLID COMPONENT | ARKRAY, Inc. (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-0860695-A9 | METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE | KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) | 2001-10-17 | — | — | EP | disclosed |
| EP-0860695-A1 | METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE | KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) | 1998-08-26 | — | — | EP | disclosed |
| EP-0017209-A1 | Substituted alkylammonium salts, their preparation and use in plant growth regulation | BASF Aktiengesellschaft (DE) | 1980-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | NPSR1 747/4885ESR1 1578/4885ESR2 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.