SCHEMBL4849374

SCHEMBL4849374

CC(=O)N(c1ccccc1)c1ccc(I)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 4/20 0.50
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.47
TSHR P16473 2/20 0.47
NPC1 O15118 2/20 0.46
APAF1 O14727 2/20 0.46
HDAC6 Q9UBN7 2/20 0.43
ALDH1A1 P00352 3/20 0.42
POLB P06746 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TDP2 O95551 1/20 0.41
NSD2 O96028 1/20 0.41
CASP3 P42574 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
HKDC1 Q2TB90 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4849735 0.94 NPSR1 (0.45) NPSR1KMT2AMEN1TSHRNPC1
SCHEMBL5489120 0.91 MAPT (0.46) NPSR1KMT2AMEN1TSHRNPC1
SCHEMBL8044893 0.89 NPSR1 (0.61) NPSR1KMT2AMEN1TSHRNPC1
SCHEMBL741752 0.87 NPSR1 (0.64) NPSR1KMT2AMEN1TSHRNPC1
Hydrochloric Acid SCHEMBL8550497 0.85 NPSR1 (0.61) NPSR1KMT2AMEN1TSHRNPC1
SCHEMBL1471487 0.83 NPSR1 (0.54) NPSR1KMT2AMEN1TSHRNPC1
SCHEMBL2095874 0.83 NPSR1 (0.54) NPSR1KMT2AMEN1TSHRNPC1
SCHEMBL2095872 0.82 NPSR1 (0.52) NPSR1KMT2AMEN1TSHRNPC1
SCHEMBL5540103 0.82 NPSR1 (0.52) NPSR1KMT2AMEN1TSHRNPC1
SCHEMBL3975700 0.82 NPSR1 (0.52) NPSR1KMT2AMEN1TSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111646917-B Preparation method of iodobenzene para-amination compound promoted by m-chloroperoxybenzoic acid 湖北工业大学 2023-04-25 CN disclosed
CN-111646917-A Preparation method of iodobenzene para-aminated compound promoted by m-chloroperoxybenzoic acid 湖北工业大学 2020-09-11 CN disclosed
US-7402701-B2 Organic EL devices and production process thereof DENSO CORPORATION (JP) 2008-07-22 US disclosed
US-7357992-B2 Organic EL devices and production process thereof DENSO CORPORATION (JP) 2008-04-15 US disclosed
US-20070293704-A1 Organic EL devices and production process thereof DENSO CORPORATION (JP) 2007-12-20 US disclosed
US-20050064237-A1 Organic EL devices and production process thereof DENSO CORPORATION (JP) 2005-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293704-A1 Organic EL devices and production process thereof EML4, ELAVL1, OR10J3 NPSR1 4816/4885KMT2A 1846/4885MEN1 3049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.