SCHEMBL397619

SCHEMBL397619

CCCc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
ALDH1A1 P00352 6/20 0.50
HPGD P15428 5/20 0.50
HSD17B10 Q99714 4/20 0.50
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 4/20 0.46
CYP1A2 P05177 4/20 0.44
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
ERBB2 P04626 1/20 0.42
FYN P06241 1/20 0.42
MAOA P21397 1/20 0.42
ACHE P22303 1/20 0.42
AHR P35869 1/20 0.42
THRB P10828 1/20 0.41
POLB P06746 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29743239 0.89 MEN1 (0.63) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL719581 0.89 MEN1 (0.63) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL21240683 0.88 MEN1 (0.46) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL28773743 0.87 MEN1 (0.45) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL728204 0.87 MEN1 (0.61) KMT2AMEN1ALDH1A1HPGDHSD17B10
Diphenylmethane SCHEMBL10561046 0.86 MEN1 (0.49) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL9299020 0.85 MEN1 (0.59) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL30345593 0.85 MEN1 (0.59) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL9931458 0.85 MEN1 (0.59) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL4585929 0.85 MEN1 (0.59) KMT2AMEN1ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111517999-B Alkyl sulfone compound and synthesis method and application thereof 华东师范大学 2022-04-05 CN claimed
CN-111517999-A Alkyl sulfone compound and synthesis method and application thereof 华东师范大学 2020-08-11 CN claimed
EP-0205247-B1 DERIVATIVES OF QUINUCLIDINE STATE OF ISRAEL, REPRESENTED BY PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1992-12-16 EP claimed
EP-0205247-A2 Derivatives of quinuclidine STATE OF ISRAEL, REPRESENTED BY PRIME MINISTER'S OFFICE, ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) 1986-12-17 EP claimed
US-3966674-A PROPYLFLUORANTHENE, PROPYLPYRENE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-06-29 US claimed
US-3933772-A ALKYLPYRENE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-01-20 US claimed
CN-111517999-B Alkyl sulfone compound and synthesis method and application thereof 华东师范大学 2022-04-05 CN disclosed
CN-111517999-A Alkyl sulfone compound and synthesis method and application thereof 华东师范大学 2020-08-11 CN disclosed
CN-106872418-B Detect fluorescence probe system, probe synthesis and the application of phosphorylated protein 中国科学院大连化学物理研究所 2019-04-09 CN disclosed
CN-106872418-A Detect fluorescence probe system, probe synthesis and the application of phosphorylated protein 中国科学院大连化学物理研究所 2017-06-20 CN disclosed
EP-2132997-B1 Shield structure for helmet or goggles, and helmet comprising such shield structure SHOEI CO LTD (JP) 2012-01-25 EP disclosed
US-8032946-B2 Shield structure for helmet or goggles, and helmet comprising such shield structure SHOEI CO., LTD. (JP) 2011-10-11 US disclosed
US-7745396-B2 Use of SERP-1 as an antiplatelet agent VIRON THERAPEUTICS INC. (CA) 2010-06-29 US disclosed
EP-0760093-B1 EMISSION QUENCHING SENSORS MINNESOTA MINING & MFG (US) 1998-04-08 EP disclosed
EP-0760093-A1 EMISSION QUENCHING SENSORS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-05 EP disclosed
CN-1133088-A Emission-suppressing sensor MINNESOTA MINING & MFG (US) 1996-10-09 CN disclosed
WO-1995010766-A1 EMISSION QUENCHING SENSORS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-20 WO disclosed
US-4016135-A STABILIZATION OF A POLYMERIC RESIN WITH AN ALKYL SUBSTITUTED TETRACYCLIC COMPOUND KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-04-05 US disclosed
US-3966674-A PROPYLFLUORANTHENE, PROPYLPYRENE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-06-29 US disclosed
US-3933772-A ALKYLPYRENE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-01-20 US disclosed