Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 5/20 | 0.41 |
| ▸ | NMT2 | O60551 | 4/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27535723 | 0.94 | SLC6A5 (0.45) | LMNATHRBKMT2AALDH1A1MEN1 | |
| SCHEMBL3717425 | 0.94 | SLC6A5 (0.45) | LMNATHRBKMT2AALDH1A1MEN1 | |
| SCHEMBL2182070 | 0.89 | SLC6A5 (0.40) | LMNATHRBKMT2AALDH1A1MEN1 | |
| SCHEMBL3758242 | 0.87 | SLC6A5 (0.55) | KMT2AMEN1SLC6A5PLA2G2CPLA2G10 | |
| SCHEMBL8846585 | 0.87 | SLC6A5 (0.55) | KMT2AMEN1SLC6A5PLA2G2CPLA2G10 | |
| SCHEMBL25183394 | 0.85 | PLA2G2C (0.49) | LMNAKMT2AMEN1CYP2D6NFKB1 | |
| SCHEMBL25173449 | 0.85 | PLA2G2C (0.49) | LMNAKMT2AMEN1CYP2D6NFKB1 | |
| SCHEMBL25186456 | 0.85 | PLA2G2C (0.49) | LMNAKMT2AMEN1CYP2D6NFKB1 | |
| SCHEMBL7186702 | 0.85 | SLC6A5 (0.53) | KMT2AMEN1SLC6A5PLA2G2CPLA2G10 | |
| SCHEMBL3628190 | 0.84 | KMT2A (0.46) | LMNATHRBKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217621-B1 | INSULIN DERIVATIVE | NOVO NORDISK AS (DK) | 2015-04-22 | — | — | EP | disclosed |
| EP-2058330-A1 | Insulin derivative | NOVO NORDISK A/S (DK) | 2009-05-13 | — | — | EP | disclosed |