Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815238 | 0.95 | ADAMTS5 (0.83) | ADAMTS5ADAMTS4 | |
| SCHEMBL1815702 | 0.94 | ADAMTS5 (0.81) | ADAMTS5ADAMTS4 | |
| SCHEMBL1815211 | 0.94 | ADAMTS5 (0.84) | ADAMTS5ADAMTS4 | |
| SCHEMBL1813659 | 0.86 | ADAMTS5 (1.00) | ADAMTS5ADAMTS4 | |
| SCHEMBL1813190 | 0.86 | ADAMTS5 (1.00) | ADAMTS5ADAMTS4 | |
| SCHEMBL1813188 | 0.86 | ADAMTS5 (1.00) | ADAMTS5ADAMTS4 | |
| SCHEMBL1812138 | 0.85 | ADAMTS5 (0.87) | ADAMTS5ADAMTS4 | |
| SCHEMBL1813427 | 0.85 | ADAMTS5 (0.79) | ADAMTS5ADAMTS4 | |
| SCHEMBL1813564 | 0.85 | ADAMTS5 (0.80) | ADAMTS5ADAMTS4 | |
| SCHEMBL1814823 | 0.84 | ADAMTS5 (0.84) | ADAMTS5ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2056823-A2 | 8-HYDROXYQUINOLINE COMPOUNDS AND METHODS THEREOF | Wyeth (US) | 2009-05-13 | — | — | EP | claimed |
| WO-2008024922-A2 | 8-HYDROXYQUINOLINE COMPOUNDS AND METHODS THEREOF | WYETH (US) | 2008-02-28 | — | — | WO | claimed |
| EP-2056823-A2 | 8-HYDROXYQUINOLINE COMPOUNDS AND METHODS THEREOF | Wyeth (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008024922-A2 | 8-HYDROXYQUINOLINE COMPOUNDS AND METHODS THEREOF | WYETH (US) | 2008-02-28 | — | — | WO | disclosed |