Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610369 | 0.78 | CES2 (0.50) | HPGDCES2CES1SRCCYP2D6 | |
| SCHEMBL10991107 | 0.76 | CES2 (0.54) | HPGDCES2CES1SRCCYP2D6 | |
| SCHEMBL9272891 | 0.75 | SRC (0.50) | HPGDSRCCYP2D6LMNAMAPT | |
| SCHEMBL9806266 | 0.75 | HPGD (0.48) | HPGDSRCCYP2D6LMNAALDH1A1 | |
| SCHEMBL2318477 | 0.74 | CYP2D6 (0.45) | HPGDSRCCYP2D6LMNAKMT2A | |
| SCHEMBL2249346 | 0.73 | HPGD (0.63) | HPGDCES2CES1CYP2D6LMNA | |
| SCHEMBL12468637 | 0.73 | HPGD (0.63) | HPGDCES2CES1CYP2D6LMNA | |
| SCHEMBL13849535 | 0.73 | HPGD (0.63) | HPGDCES2CES1CYP2D6LMNA | |
| SCHEMBL2163297 | 0.73 | HPGD (0.47) | HPGDCYP2D6LMNAALDH1A1CYP3A4 | |
| SCHEMBL31440500 | 0.73 | SRC (0.54) | HPGDCES2CES1SRCCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1130038-B1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2009-05-06 | — | — | EP | claimed |
| US-20050263745-A1 | Method of preparing a ceramic artificial crown and a preparation kit used therefor | TOKUYAMA CORPORATION (JP) | 2005-12-01 | — | — | US | claimed |
| EP-1130038-A1 | CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2001-09-05 | — | — | EP | claimed |
| US-8529789-B2 | Curable composition | TOKUYAMA CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| EP-1130038-B1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2009-05-06 | — | — | EP | disclosed |
| US-20050263745-A1 | Method of preparing a ceramic artificial crown and a preparation kit used therefor | TOKUYAMA CORPORATION (JP) | 2005-12-01 | — | — | US | disclosed |
| EP-1130038-A1 | CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2001-09-05 | — | — | EP | disclosed |