SCHEMBL3976573

SCHEMBL3976573

Oc1c(-c2ccccc2)ccc(-c2ccccc2)c1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.61
HDAC2 Q92769 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
HDAC6 Q9UBN7 1/20 0.61
BACE1 P56817 2/20 0.60
ALDH1A1 P00352 5/20 0.57
BCL2L1 Q07817 2/20 0.57
HSD17B10 Q99714 2/20 0.57
HPGD P15428 2/20 0.57
ALOX5 P09917 1/20 0.56
HNF4A P41235 1/20 0.54
ESR2 Q92731 1/20 0.50
MMP3 P08254 1/20 0.48
PDE4B Q07343 3/20 0.45
PDE4A P27815 2/20 0.45
PDE4C Q08493 2/20 0.45
PDE4D Q08499 2/20 0.45
PTPN1 P18031 1/20 0.45
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79394 0.89 BACE1 (0.56) HDAC4HDAC2HDAC8HDAC6BACE1
SCHEMBL27847644 0.89 BCL2L1 (0.67) HDAC4HDAC2HDAC8HDAC6BACE1
SCHEMBL30669867 0.89 BACE1 (0.56) HDAC4HDAC2HDAC8HDAC6BACE1
SCHEMBL28421582 0.87 BACE1 (0.54) HDAC4HDAC2HDAC8HDAC6BACE1
Methane SCHEMBL29224625 0.87 BACE1 (0.54) HDAC4HDAC2HDAC8HDAC6BACE1
SCHEMBL8724544 0.87 HSD17B10 (0.52) HDAC4HDAC2HDAC8HDAC6BACE1
SCHEMBL4647831 0.86 HDAC4 (0.54) HDAC4HDAC2HDAC8HDAC6BACE1
SCHEMBL10617137 0.85 ESR2 (0.55) HDAC4HDAC2HDAC8HDAC6BACE1
SCHEMBL380375 0.85 CYP2A6 (0.50) HDAC4HDAC2HDAC8HDAC6BACE1
SCHEMBL8853081 0.85 ALDH1A1 (0.50) HDAC4HDAC2HDAC8HDAC6BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115346710-A High-thermal-conductivity multi-rubber powder mica tape and preparation method thereof 苏州巨峰电气绝缘系统股份有限公司 2022-11-15 CN claimed
US-6476179-B1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-11-05 US claimed
JP-3097725-A None JP disclosed
CN-117295619-A Non-pneumatic tire 株式会社普利司通 2023-12-26 CN disclosed
CN-116917410-A Antiviral resin composition containing hydrophilic polymer and molded body 东丽塞拉尼斯有限公司 2023-10-20 CN disclosed
CN-109757104-B Thermoplastic resin composition and metal joint and method for producing same 东丽先端材料研究开发(中国)有限公司 2023-10-13 CN disclosed
CN-116848174-A Antiviral resin composition and molded article 东丽塞拉尼斯有限公司 2023-10-03 CN disclosed
CN-116745476-A Fabric, fabric body, and seat 东丽株式会社 2023-09-12 CN disclosed
CN-116194510-A End-modified polyester resin, composition, molded article, and process for producing the same 东丽先端材料研究开发(中国)有限公司 2023-05-30 CN disclosed
CN-111391459-B Multilayer film, laminate, airbag, and method for producing laminate 日东电工株式会社(JP) 2023-01-13 CN disclosed
CN-115516033-A Thermoplastic elastomer composition for tire and tire 住友橡胶工业株式会社 2022-12-23 CN disclosed
EP-0896975-B1 POLYCARBONATE, AND MOLDING AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN CO (JP) 2003-06-04 EP disclosed
EP-1288242-A2 Polycarbonate, and molding and electrophotograpic photoreceptor prepared therefrom Idemitsu Kosan Co., Ltd. (JP) 2003-03-05 EP disclosed
EP-1178068-A1 PROCESSES FOR PRODUCING RAW POLYCARBONATE RESIN MATERIAL AND PRODUCING POLYCARBONATE RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-02-06 EP disclosed
US-6136521-A POLYORGANOSILOXANE-CONTAINING POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2000-10-24 US disclosed
EP-0896975-A1 POLYCARBONATE, AND MOLDING AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1999-02-17 EP disclosed
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed
JP-H0397725-A PRODUCTION OF POLYESTER SEKISUI CHEM CO LTD 1991-04-23 JP disclosed
EP-0344099-A2 A polyester and an article made of the same SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-11-29 EP disclosed
US-3947468-A Production of dibenzopyrans, their isomeric fluorenols and dibenzothiopyrans GENERAL ELECTRIC COMPANY (US) 1976-03-30 US disclosed