Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431795 | 0.81 | SCD (0.36) | EPHX2HDAC6DPP4DPP8 | |
| SCHEMBL8840142 | 0.78 | PTPN1 (0.39) | PTPN1DPP4DPP8ELANE | |
| SCHEMBL17040253 | 0.75 | PTPN1 (0.50) | PTPN1 | |
| Hydrochloric Acid SCHEMBL11596232 | 0.73 | PTPN1 (0.48) | PTPN1 | |
| SCHEMBL31292266 | 0.71 | EPHX2 (0.36) | EPHX2HDAC6 | |
| SCHEMBL8840233 | 0.67 | PTPN1 (0.66) | PTPN1 | |
| SCHEMBL22116750 | 0.67 | NPC1 (0.63) | PTPN1HDAC6 | |
| SCHEMBL30024561 | 0.67 | EPHX2 (0.38) | EPHX2HDAC6 | |
| SCHEMBL16056974 | 0.66 | HDAC6 (0.37) | EPHX2HDAC6ELANE | |
| SCHEMBL18760057 | 0.66 | HDAC6 (0.47) | EPHX2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060030-A1 | HETEROARYL-SUBSTITUTED 2-PYRIDINYLMETHYLAMINE DERIVATIVES | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2009-05-14 | — | — | WO | disclosed |
| EP-2058306-A1 | Heteroaryl-substituted 2-pyridinyl-methylamine derivatives | SCHWARZ PHARMA AG (DE) | 2009-05-13 | — | — | EP | disclosed |