Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11596232 | 0.97 | PTPN1 (0.48) | PTPN1CYP1A2NR4A2NPC1RAB9A | |
| SCHEMBL18364475 | 0.87 | PTPN1 (0.42) | PTPN1CYP1A2NR4A2 | |
| SCHEMBL185561 | 0.81 | — | — | |
| SCHEMBL8334992 | 0.81 | — | — | |
| SCHEMBL29156966 | 0.79 | PTPN1 (0.41) | PTPN1 | |
| Hydrochloric Acid SCHEMBL22436543 | 0.79 | PTPN1 (0.41) | PTPN1ALDH1A1 | |
| SCHEMBL22436525 | 0.79 | PTPN1 (0.41) | PTPN1ALDH1A1 | |
| Potassium SCHEMBL834916 | 0.79 | PTPN1 (0.41) | PTPN1ALDH1A1 | |
| SCHEMBL8840142 | 0.75 | PTPN1 (0.39) | PTPN1 | |
| SCHEMBL13302546 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283574-A1 | Multivariate and other metal-organic frameworks, and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | US | disclosed |
| US-10287304-B2 | Acid, solvent, and thermal resistant metal-organic frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-05-14 | — | — | US | disclosed |
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-01-12 | — | — | US | disclosed |
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-01-12 | — | — | US | disclosed |
| WO-2015127033-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210283574-A1 | Multivariate and other metal-organic frameworks, and uses thereof | AQP3, AQP4, AQP1 | PTPN1 4462/4885CYP1A2 4492/4885NR4A2 3763/4885 |
| US-10287304-B2 | Acid, solvent, and thermal resistant metal-organic frameworks | HAO2, ASF1A, FTO | PTPN1 4354/4885CYP1A2 2176/4885NR4A2 3658/4885 |
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | HAO2, ASF1A, FTO | PTPN1 4354/4885CYP1A2 2176/4885NR4A2 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.