Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 1.00 |
| ▸ | DRD2 | P14416 | 3/20 | 0.68 |
| ▸ | DRD4 | P21917 | 3/20 | 0.68 |
| ▸ | DRD3 | P35462 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972171 | 0.91 | HTR1A (1.00) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL3982034 | 0.89 | HTR1A (1.00) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL3977270 | 0.85 | HTR1A (0.76) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL3972879 | 0.83 | HTR1A (0.77) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL14164158 | 0.82 | HTR1A (0.89) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL5185385 | 0.82 | HTR1A (1.00) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL3982035 | 0.82 | HTR1A (1.00) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL27561954 | 0.82 | HTR1A (0.77) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL3975692 | 0.81 | HTR1A (0.74) | HTR1ADRD2DRD4DRD3 | |
| SCHEMBL4085366 | 0.81 | HTR1A (0.76) | HTR1ADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060030-A1 | HETEROARYL-SUBSTITUTED 2-PYRIDINYLMETHYLAMINE DERIVATIVES | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2009-05-14 | — | — | WO | disclosed |
| EP-2058306-A1 | Heteroaryl-substituted 2-pyridinyl-methylamine derivatives | SCHWARZ PHARMA AG (DE) | 2009-05-13 | — | — | EP | disclosed |