Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3976338 | 0.91 | CNR2 (0.45) | CNR2CNR1KDM4EPDE4APDE4B | |
| SCHEMBL3978510 | 0.88 | CNR2 (0.44) | CNR2CNR1PDE4APDE4BPDE4C | |
| SCHEMBL3976822 | 0.83 | ALDH1A1 (0.38) | CNR2CNR1KDM4ESLC9A1 | |
| SCHEMBL13886068 | 0.80 | CNR2 (0.48) | CNR2CNR1PDE4APDE4BPDE4C | |
| SCHEMBL13885626 | 0.78 | NPC1 (0.53) | CNR2CNR1PDE4APDE4BPDE4C | |
| SCHEMBL13885733 | 0.76 | CNR2 (0.51) | CNR2CNR1PDE4APDE4BPDE4C | |
| SCHEMBL9342889 | 0.74 | CNR2 (0.58) | CNR2CNR1KDM4EPDE4APDE4B | |
| SCHEMBL3976415 | 0.74 | ALDH1A1 (0.36) | CNR2CNR1KDM4EHPGDHTT | |
| SCHEMBL4404025 | 0.74 | CNR2 (0.45) | CNR2CNR1KDM4EPDE4APDE4B | |
| SCHEMBL3978568 | 0.73 | CNR2 (0.44) | CNR2CNR1KDM4EPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053799-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-04-30 | — | — | WO | claimed |
| WO-2009053799-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009053799-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-04-30 | — | — | WO | disclosed |