⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081210 | 0.74 | — | — | |
| Propionamide SCHEMBL4230074 | 0.73 | — | — | |
| SCHEMBL3603565 | 0.70 | — | — | |
| SCHEMBL13381508 | 0.70 | — | — | |
| SCHEMBL8099258 | 0.70 | — | — | |
| Propionic Acid SCHEMBL3795566 | 0.70 | — | — | |
| Propionamide SCHEMBL2722745 | 0.70 | — | — | |
| Propionic Acid SCHEMBL1896909 | 0.70 | — | — | |
| SCHEMBL3239168 | 0.70 | — | — | |
| Propionic Acid SCHEMBL5054297 | 0.70 | FFAR3 (0.77) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117942294-A | Facial cleanser composition containing dendrobium candidum extract and preparation method thereof | 澳宝化妆品（惠州）有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117334855-A | Zwitterionic polymer coated silicon carbon material and preparation method and application thereof | 碳一新能源集团有限责任公司 | 2024-01-02 | — | — | CN | claimed |
| CN-114042005-B | Suspension composition containing lamellar liquid crystal and preparation process thereof | 广州天赐高新材料股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-116496187-A | High-stability ionic polymer antistatic agent and preparation method thereof | 杭州临安德昌静电科技有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-116211726-A | Sulfate-free hair composition and method for evaluating washability | 九江天赐高新材料有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-115300405-A | Hair composition with color protection effect and preparation method and application thereof | 清远天赐高新材料有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-108424760-B | CO suitable for compact oil reservoir2Sensitive fracturing-displacement system and preparation method and application method thereof | 中国石油大学(华东) | 2021-02-23 | — | — | CN | claimed |
| CN-101522661-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (VG) | 2009-09-02 | — | — | CN | claimed |
| CN-101454327-A | Azolopyrimidines as inhibitors of cannabinoid 1 activity | IRM LLC (BM) | 2009-06-10 | — | — | CN | claimed |
| US-20070275986-A1 | Use of purine derivatives for the production of medicaments for the treatment of mucoviscidosis and diseases related to protein addressing errors in cells | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-11-29 | — | — | US | claimed |
| EP-1802310-A1 | USE OF PURINE DERIVATIVES FOR THE PRODUCTION OF MEDICAMENTS FOR THE TREATMENT OF MUCOVISCIDOSIS AND DISEASES RELATED TO PROTEIN ADDRESSING ERRORS IN CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-07-04 | — | — | EP | claimed |
| WO-2006042949-A1 | USE OF PURINE DERIVATIVES FOR THE PRODUCTION OF MEDICAMENTS FOR THE TREATMENT OF MUCOVISCIDOSIS AND DISEASES RELATED TO PROTEIN ADDRESSING ERRORS IN CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2006-04-27 | — | — | WO | claimed |
| EP-0165580-A2 | Resin compositions and products using the same | Takeda Chemical Industries, Ltd. (JP) | 1985-12-27 | — | — | EP | claimed |
| US-4100193-A | MICROBIOCIDES, ALGAE INHIBITORS | MERCK & CO., INC. (US) | 1978-07-11 | — | — | US | claimed |
| US-4065497-A | MICROBIOCIDES, ALGICIDES | MERCK & CO., INC. (US) | 1977-12-27 | — | — | US | claimed |
| US-4060639-A | Broad spectrum antibacterial compositions containing tris-(hydroxymethyl)-aminoethane and dicycloaliphatic-alkyl polyamines | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | claimed |
| US-4058624-A | Broad spectrum antibacterial compositions containing tris (hydroxymethyl)-aminomethane and diphenyl and loweralkyl substituted diphenyl polyamines | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | claimed |
| US-4058625-A | Broad spectrum antimicrobial compositions containing tris-(hydroxymethyl)aminomethane and polyamines | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | claimed |
| US-4049417-A | CONTAINING CYCLOHEXYL OR CYCLOHEXENYL RINGS | MERCK & CO., INC. (US) | 1977-09-20 | — | — | US | claimed |
| CN-115300405-B | Hair composition with color protection effect and preparation method and application thereof | 清远天赐高新材料有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117942294-A | Facial cleanser composition containing dendrobium candidum extract and preparation method thereof | 澳宝化妆品（惠州）有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117883317-A | Suspension system, transparent shampoo and preparation method thereof | 广州环亚化妆品科技股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117334855-A | Zwitterionic polymer coated silicon carbon material and preparation method and application thereof | 碳一新能源集团有限责任公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-114983864-B | Salicylic acid transparent bath foam of suspension system and preparation method thereof | 广州环亚化妆品科技股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116496187-A | High-stability ionic polymer antistatic agent and preparation method thereof | 杭州临安德昌静电科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116211726-A | Sulfate-free hair composition and method for evaluating washability | 九江天赐高新材料有限公司 | 2023-06-06 | — | — | CN | disclosed |
| WO-2023041757-A1 | NEW COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2023-03-23 | — | — | WO | disclosed |
| EP-1802310-B1 | USE OF PURINE DERIVATIVES FOR THE PRODUCTION OF MEDICAMENTS FOR THE TREATMENT OF MUCOVISCIDOSIS AND DISEASES RELATED TO PROTEIN ADDRESSING ERRORS IN CELLS | MANROS THERAPEUTICS (FR) | 2014-12-17 | — | — | EP | disclosed |
| US-8492420-B2 | Use of purine derivatives for the production of medicaments for the treatment of mucoviscidosis and diseases related to protein addressing errors in cells | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2013-07-23 | — | — | US | disclosed |
| US-20090264411-A1 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-22 | — | — | US | disclosed |
| CN-101522661-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (VG) | 2009-09-02 | — | — | CN | disclosed |
| WO-2009093013-A1 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009093009-A1 | FUSED TRICYCLIC THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2009-07-30 | — | — | WO | disclosed |
| CN-101454327-A | Azolopyrimidines as inhibitors of cannabinoid 1 activity | IRM LLC (BM) | 2009-06-10 | — | — | CN | disclosed |
| EP-2054417-A2 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB Pharma S.A. (BE) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008020206-A2 | FUSED THIOPHENE DERIVATIVES AS MEK INHIBITORS | UCB PHARMA S.A. (BE) | 2008-02-21 | — | — | WO | disclosed |
| US-20070275986-A1 | Use of purine derivatives for the production of medicaments for the treatment of mucoviscidosis and diseases related to protein addressing errors in cells | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-11-29 | — | — | US | disclosed |
| EP-1802310-A1 | USE OF PURINE DERIVATIVES FOR THE PRODUCTION OF MEDICAMENTS FOR THE TREATMENT OF MUCOVISCIDOSIS AND DISEASES RELATED TO PROTEIN ADDRESSING ERRORS IN CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-07-04 | — | — | EP | disclosed |
| US-20060160154-A1 | Materials and methods for detection and treatment of breast cancer | MATRITECH, INC. (US) | 2006-07-20 | — | — | US | disclosed |
| EP-0923740-B1 | METHODS AND COMPOSITIONS FOR THE DETECTION OF CERVICAL CANCER | MATRITECH INC (US) | 2006-07-05 | — | — | EP | disclosed |
| CN-1775794-A | Azitromycin double salts and their preparing method and use | XI AN XIN AN MEDICINAL SCI & T (CN) | 2006-05-24 | — | — | CN | disclosed |
| WO-2006042949-A1 | USE OF PURINE DERIVATIVES FOR THE PRODUCTION OF MEDICAMENTS FOR THE TREATMENT OF MUCOVISCIDOSIS AND DISEASES RELATED TO PROTEIN ADDRESSING ERRORS IN CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2006-04-27 | — | — | WO | disclosed |
| US-6936424-B1 | Materials and methods for detection and treatment of breast cancer | MATRITECH, INC. (US) | 2005-08-30 | — | — | US | disclosed |
| US-20050164313-A1 | Methods and compositions for the detection of cervical cancer | KEESEE SUSAN K (US) | 2005-07-28 | — | — | US | disclosed |
| US-6803189-B2 | BINDING LABELED ANTIBODY TO PROTEIN; MEASUREMENT; CALIBRATION | MATRITECH, INC. | 2004-10-12 | — | — | US | disclosed |
| WO-2002075314-A9 | DETECTION AND TREATMENT OF PROSTATE CANCER | MATRITECH INC (US) | 2003-11-20 | — | — | WO | disclosed |
| US-20030157482-A1 | METHODS AND COMPOSITIONS FOR THE DETECTION OF CERVICAL CANCER | ALERE SAN DIEGO, INC. (FKA BIOSITE INC. OR FKA CHOLESTECH CORP. OR FKA HEMOSENSE INC. OR FKA INVERNESS MEDICAL-BIOSTAR INC. OR FKA ISCHEMIA TECHNOLOGIES, INC. OR FKA TWISTDX, INC.) | 2003-08-21 | — | — | US | disclosed |
| US-20020164664-A1 | Detection and treatment of prostate cancer | MATRITECH, INC. | 2002-11-07 | — | — | US | disclosed |
| WO-2002078636-A2 | DETECTION AND TREATMENT OF COLORECTAL CANCER | MATRITECH, INC. (US) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002075314-A2 | DETECTION AND TREATMENT OF PROSTATE CANCER | MATRITECH, INC. (US) | 2002-09-26 | — | — | WO | disclosed |
| EP-1232177-A2 | METHODS AND COMPOSITIONS FOR DETECTION AND TREATMENT OF BREAST CANCER, BASED ON BREAST CANCER-ASSOCIATED POLYPEPTIDES | Matritech, Inc. (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036470-A2 | METHODS AND COMPOSITIONS FOR DETECTION AND TREATMENT OF BREAST CANCER, BASED ON BREAST CANCER-ASSOCIATED POLYPEPTIDES | MATRITECH, INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| US-6027905-A | SCREENING FOR CERVIAL CANCER IN A HUMAN BY DETECTING THE PRESENCE OF A PROTEIN OF GIVEN AMINO ACID SEQUENCE IN A SAMPLE OBTAINED FROM THE HUMAN; PRESENCE INDICATES CERVICAL CANCER | MATRITECH, INC. (US) | 2000-02-22 | — | — | US | disclosed |
| EP-0923740-A2 | METHODS AND COMPOSITIONS FOR THE DETECTION OF CERVICAL CANCER | MATRITECH, INC. (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5858683-A | DETERMINING PRESENCE OF NON-CHROMATIN PROTEIN IN BIOLOGICAL SAMPLE (PAP SMEARS) BY IMMUNOASSAY OR TWO-DIMENSIONAL ELECTROPHORESIS; ACCURATE RAPID DIAGNOSIS BEFORE METASTASIS OCCURS | MATRITECH, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0856052-A1 | ANTISENSE OLIGONUCLEOTIDE CHEMOTHERAPY FOR BENIGN HYPERPLASIA OR CANCER OF THE PROSTATE | University of Massachusetts (US) | 1998-08-05 | — | — | EP | disclosed |
| EP-0851919-A1 | ANTISENSE OLIGONUCLEOTIDE CHEMOTHERAPY FOR BENIGN HYPERPLASIA OR CANCER OF THE PROSTATE | University of Massachusetts Worcester (US) | 1998-07-08 | — | — | EP | disclosed |
| WO-1998009170-A2 | METHODS AND COMPOSITIONS FOR THE DETECTION OF CERVICAL CANCER | MATRITECH, INC. (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1997011170-A1 | ANTISENSE OLIGONUCLEOTIDE CHEMOTHERAPY FOR BENIGN HYPERPLASIA OR CANCER OF THE PROSTATE | WORCESTER FOUNDATION FOR BIOMEDICAL RESEARCH (US) | 1997-03-27 | — | — | WO | disclosed |
| WO-1997011172-A1 | ANTISENSE OLIGONUCLEOTIDE CHEMOTHERAPY FOR BENIGN HYPERPLASIA OR CANCER OF THE PROSTATE | UNIVERSITY OF MASSACHUSETTS (US) | 1997-03-27 | — | — | WO | disclosed |
| EP-0715649-A1 | PROCESS FOR PREPARING CONCENTRATED SURFACTANT MIXTURES CONTAINING MAGNESIUM | PROCTER & GAMBLE (US) | 1996-06-12 | — | — | EP | disclosed |
| EP-0548265-B1 | MILD SHAMPOO COMPOSITIONS | PROCTER & GAMBLE (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1995006103-A1 | PROCESS FOR PREPARING CONCENTRATED SURFACTANT MIXTURES CONTAINING MAGNESIUM | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-02 | — | — | WO | disclosed |
| US-5229412-A | Administering carrier with anxiolytic derivatives of N-(3-/4-indolyloxy/-2-hydroxypropyl)-1,8-diamino-p-menthane | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1993-07-20 | — | — | US | disclosed |
| WO-1992004882-A1 | MILD SHAMPOO COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-04-02 | — | — | WO | disclosed |
| EP-0338877-A1 | Selective binding compounds for 5-hydroxytryptamine 1-A-receptors and pharmaceutical compositions containing them | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1989-10-25 | — | — | EP | disclosed |
| US-4808412-A | BIOACTIVE INGREDIENT DISPERSED IN BASIC POLYMER | EASTMAN KODAK COMPANY (US) | 1989-02-28 | — | — | US | disclosed |
| US-4340756-A | Polyamine compounds as antibacterial agents | MERCK & CO., INC. (US) | 1982-07-20 | — | — | US | disclosed |
| US-4260760-A | BACTERICIDES, ALGICIDES | MERCK & CO., INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4172094-A | Polyamine compounds | MERCK & CO., INC. (US) | 1979-10-23 | — | — | US | disclosed |
| US-4100193-A | MICROBIOCIDES, ALGAE INHIBITORS | MERCK & CO., INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4091020-A | CONDENSATION, CATALYTIC DECARBOXYLATION | MERCK & CO., INC. (US) | 1978-05-23 | — | — | US | disclosed |
| US-4065497-A | MICROBIOCIDES, ALGICIDES | MERCK & CO., INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-4061775-A | Polyamine compounds as antibacterial agents | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4060639-A | Broad spectrum antibacterial compositions containing tris-(hydroxymethyl)-aminoethane and dicycloaliphatic-alkyl polyamines | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4058624-A | Broad spectrum antibacterial compositions containing tris (hydroxymethyl)-aminomethane and diphenyl and loweralkyl substituted diphenyl polyamines | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4058625-A | Broad spectrum antimicrobial compositions containing tris-(hydroxymethyl)aminomethane and polyamines | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4049417-A | CONTAINING CYCLOHEXYL OR CYCLOHEXENYL RINGS | MERCK & CO., INC. (US) | 1977-09-20 | — | — | US | disclosed |
| US-4003934-A | ANTIMICROBIAL AGENTS, ALGAE INHIBITORS | MERCK & CO., INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-4003934-A | ANTIMICROBIAL AGENTS, ALGAE INHIBITORS | MERCK & CO., INC. (US) | 1977-01-18 | — | — | US | disclosed |