SCHEMBL3977955

SCHEMBL3977955

Oc1ccc(C23CC4CC(C2)CC(c2ccc(O)c(Cl)c2)(C4)C3)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
POLB P06746 1/20 0.59
GAA P10253 1/20 0.59
GFER P55789 1/20 0.59
SPHK2 Q9NRA0 2/20 0.46
SPHK1 Q9NYA1 2/20 0.46
ALDH1A1 P00352 3/20 0.45
LMNA P02545 3/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
EPHX2 P34913 1/20 0.43
PGR P06401 2/20 0.42
ESR1 P03372 1/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14829050 0.91 MEN1 (0.71) MEN1KMT2APOLBGAAGFER
SCHEMBL1972365 0.86 MEN1 (0.79) MEN1KMT2APOLBGAAGFER
SCHEMBL1237159 0.81 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL3975182 0.81 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL31544676 0.81 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL3975212 0.81 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL29485576 0.81 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL2708128 0.81 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL3975973 0.80 MEN1 (0.42) MEN1KMT2APOLBGAAGFER
SCHEMBL22453702 0.80 PTPN11 (0.45) MEN1KMT2APOLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed