Sorbic Acid

Sorbic Acid

SCHEMBL3978397

CC=CC=CC(=O)O.Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)cccc2s1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbic Acid SCHEMBL3978395 1.00 TRPV1 (0.63) TRPV1
Amg-517 SCHEMBL4255926 0.88 TRPV1 (0.84) TRPV1
Amg-517 SCHEMBL4255928 0.88 TRPV1 (0.84) TRPV1
SCHEMBL1038985 0.87 TRPV1 (0.68) TRPV1
SCHEMBL4255931 0.81 TRPV1 (0.69) TRPV1
SCHEMBL1040492 0.80 TRPV1 (0.70) TRPV1
SCHEMBL9927479 0.78 TRPV1 (0.70) TRPV1
Trifluoroacetic Acid SCHEMBL1044061 0.78 TRPV1 (0.54) TRPV1
Trifluoroacetic Acid SCHEMBL1043105 0.78 TRPV1 (0.68) TRPV1
Trifluoroacetic Acid SCHEMBL1040730 0.78 TRPV1 (0.68) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2056798-A2 SORBIC ACID ANALOG CO-CRYSTALS Amgen, Inc (US) 2009-05-13 EP disclosed
WO-2008024437-A2 SORBIC ACID ANALOG CO-CRYSTALS AMGEN INC. (US) 2008-02-28 WO disclosed
US-20080051453-A1 Sorbic acid analog co-crystals AMGEN INC. 2008-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051453-A1 Sorbic acid analog co-crystals SORBS1, XDH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 TRPV1 863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.