Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.58 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843496 | 0.76 | CYP26A1 (0.44) | FDPSCYP26A1ALDH1A1TBXAS1 | |
| Methyl Alcohol SCHEMBL9715289 | 0.75 | FDPS (0.93) | FDPSALDH1A1GGPS1LMNABTN3A1 | |
| SCHEMBL515542 | 0.74 | FDPS (1.00) | FDPSALDH1A1GGPS1LMNABTN3A1 | |
| Water SCHEMBL28274320 | 0.73 | FDPS (0.96) | FDPSALDH1A1GGPS1LMNABTN3A1 | |
| Diethyl Hydrogen Phosphate SCHEMBL4951600 | 0.72 | FDPS (0.47) | FDPSKDM4EALDH1A1TBXAS1GGPS1 | |
| SCHEMBL10408873 | 0.72 | FDPS (0.60) | FDPSALDH1A1LMNAHMGCR | |
| SCHEMBL4962049 | 0.70 | FDPS (0.44) | FDPSCYP26A1KDM4EALDH1A1TBXAS1 | |
| Diethyl Hydrogen Phosphate SCHEMBL4952771 | 0.70 | FDPS (0.49) | FDPSKDM4EALDH1A1TBXAS1GGPS1 | |
| SCHEMBL28381527 | 0.70 | FDPS (0.76) | FDPSALDH1A1GGPS1LMNABTN3A1 | |
| SCHEMBL9961565 | 0.70 | FDPS (0.49) | FDPSCYP26A1ALDH1A1TBXAS1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | claimed |
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | disclosed |
| US-4939130-A | Substituted alkanediphosphonic acids and pharmaceutical use | CIBA-GEIGY CORPORATION (US) | 1990-07-03 | — | — | US | disclosed |