Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30868870 | 1.00 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| Hydrochloric Acid SCHEMBL31039939 | 0.98 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| Hydrochloric Acid SCHEMBL31039933 | 0.98 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL28091224 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL4176723 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL29559517 | 0.79 | SMN1; SMN2 (0.63) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL29466906 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL5550211 | 0.79 | SMN1; SMN2 (0.63) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL30139977 | 0.78 | KDM4E (0.82) | KDM4EALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL28516529 | 0.78 | KDM4E (0.82) | KDM4EALDH1A1SMN1; SMN2HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892573-A | 3-vinyl-quinoxaline-2(1H)-one derivatives acting on FGFR-1, preparation method and uses thereof | UNIV WENZHOU MEDICAL | 2015-09-09 | — | — | CN | claimed |
| EP-1272479-A2 | NOVEL COMPOUNDS FOR ENHANCING CHEMOTHERAPY | THE PENN STATE RESEARCH FOUNDATION (US) | 2003-01-08 | — | — | EP | claimed |
| US-20020013322-A1 | Novel compounds for enhancing chemotherapy | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-01-31 | — | — | US | claimed |
| WO-2001074790-A2 | NOVEL COMPOUNDS FOR ENHANCING CHEMOTHERAPY | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-10-11 | — | — | WO | claimed |
| EP-0318294-B1 | Dimeric and trimeric cationic dyes | NIPPON CHEMICAL WORKS (JP) | 1994-12-28 | — | — | EP | claimed |
| US-4181724-A | Quinoxalinone compounds useful for expanding the lumina or air passages in mammals | THE UPJOHN COMPANY (US) | 1980-01-01 | — | — | US | claimed |
| CN-117924194-A | 7-Thiocyanoquinoxalinone compound and synthesis method thereof | 延安大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-114907277-A | Process for asymmetric hydrogenation of quinoxalinones | 哈尔滨工业大学（深圳） | 2022-08-16 | — | — | CN | disclosed |
| CN-111892545-B | Green synthesis method of 1-methyl-3-alkyl quinoxalinone compound | 怀化学院 | 2021-11-05 | — | — | CN | disclosed |
| CN-111892545-A | Green synthesis method of 1-methyl-3-alkyl quinoxalinone compound | 怀化学院 | 2020-11-06 | — | — | CN | disclosed |
| CN-109988117-B | Preparation method of 3-methylquinoxaline-2 (1H) -ketone derivatives | 湖南科技学院 | 2020-09-29 | — | — | CN | disclosed |
| CN-108210385-B | A jelly-like collutory with effects of preventing dental caries, resisting bacteria, strengthening root and consolidating teeth | 山东大学 | 2020-08-18 | — | — | CN | disclosed |
| CN-108078822-B | Special white and black toothpaste | 山东大学 | 2020-06-26 | — | — | CN | disclosed |
| US-20020013322-A1 | Novel compounds for enhancing chemotherapy | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-01-31 | — | — | US | disclosed |
| WO-2001074790-A2 | NOVEL COMPOUNDS FOR ENHANCING CHEMOTHERAPY | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-10-11 | — | — | WO | disclosed |
| US-4499270-A | INHIBITING THE GROWTH OF MICROORGANISMS | RIKER LABORATORIES, INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4348521-A | BACTERICIDES, FUNGICIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-09-07 | — | — | US | disclosed |
| US-4262123-A | BRONCHODILATORS, ASTHMA, ECZEMA, URTICARIA | THE UPJOHN COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4242342-A | Quinoxalinones useful for treating atopic eczema and urticaria | THE UPJOHN COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4181724-A | Quinoxalinone compounds useful for expanding the lumina or air passages in mammals | THE UPJOHN COMPANY (US) | 1980-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013322-A1 | Novel compounds for enhancing chemotherapy | ABCB1, ABCB11, ABCC1 | KDM4E 4040/4885ALDH1A1 2236/4885SMN1; SMN2 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.