Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726368 | 0.87 | KMT2A (0.62) | KMT2ALMNASMN1; SMN2NLRP3LPAR1 | |
| SCHEMBL21807836 | 0.83 | RXFP1 (0.48) | SMN1; SMN2GAA | |
| SCHEMBL16203606 | 0.81 | KMT2A (0.79) | KMT2ARIPK1LMNASMN1; SMN2MEN1 | |
| SCHEMBL24575431 | 0.79 | KMT2A (0.54) | KMT2ALMNASMN1; SMN2NLRP3LPAR1 | |
| SCHEMBL22158291 | 0.78 | RXFP1 (0.44) | KMT2ASMN1; SMN2MEN1GAAMAPK1 | |
| SCHEMBL13925886 | 0.78 | SMN1; SMN2 (0.53) | KMT2ALMNASMN1; SMN2NLRP3MEN1 | |
| SCHEMBL11660078 | 0.77 | LPAR1 (0.43) | KMT2ARIPK1LMNASMN1; SMN2NLRP3 | |
| SCHEMBL9187652 | 0.77 | ALDH1A1 (0.50) | KMT2ALMNASMN1; SMN2MEN1GAA | |
| Acetic Acid SCHEMBL25282411 | 0.76 | KMT2A (0.54) | KMT2ALMNASMN1; SMN2NLRP3LPAR1 | |
| SCHEMBL13556567 | 0.76 | KMT2A (0.46) | KMT2ALMNASMN1; SMN2NLRP3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |