Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.58 |
| ▸ | PPARG | P37231 | 10/20 | 0.56 |
| ▸ | PPARA | Q07869 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983429 | 0.77 | PPARG (0.65) | MAPTPPARGPPARA | |
| SCHEMBL3973585 | 0.77 | PPARG (0.65) | MAPTPPARGPPARA | |
| SCHEMBL5935569 | 0.76 | MAPT (0.79) | MAPTALDH1A1HPGDTP53RXFP1 | |
| SCHEMBL3974615 | 0.75 | PPARG (0.68) | PPARGPPARA | |
| SCHEMBL3973596 | 0.74 | PPARG (0.67) | MAPTPTPN1PPARGPPARATP53 | |
| SCHEMBL3970004 | 0.74 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL7498107 | 0.74 | PTPN1 (1.00) | PTPN1PPARGPPARA | |
| SCHEMBL20553479 | 0.73 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL20553481 | 0.73 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL11951263 | 0.72 | TLR3 (0.76) | MAPTALDH1A1HPGDTP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | claimed |
| US-20060020003-A1 | Biphenyloxy-acids | WYETH (US) | 2006-01-26 | — | — | US | claimed |
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | disclosed |
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20060020003-A1 | Biphenyloxy-acids | WYETH (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020003-A1 | Biphenyloxy-acids | AHR, ARNT, NR1H4 | MAPT 4702/4885PTPN1 1495/4885PPARG 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.