SCHEMBL3979268

SCHEMBL3979268

Cc1cc(C)c(C)c(COc2cccc(-c3c(-c4ccccc4)coc3C(=O)NN)c2)c1C

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.43
CD274 Q9NZQ7 4/20 0.41
PTGER4 P35408 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3979293 0.96 FABP3 (0.41) FFAR1CD274PTGER4
SCHEMBL3983858 0.96 FFAR1 (0.42) FFAR1CD274PTGER4
SCHEMBL27605311 0.90 PTGER4 (0.44) FFAR1CD274PTGER4
SCHEMBL3982728 0.86 MAPT (0.41) FFAR1CD274PTGER4
SCHEMBL28752668 0.85 PTGER4 (0.44) FFAR1CD274PTGER4
SCHEMBL3979344 0.84 SMPD1 (0.47)
SCHEMBL3977706 0.82 TDP1 (0.41) FFAR1PTGER4
SCHEMBL3973638 0.82 FABP3 (0.43) FFAR1CD274PTGER4
SCHEMBL3976661 0.82 ADCYAP1R1 (0.39)
SCHEMBL3980972 0.82 FFAR1 (0.40) FFAR1CD274PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7514452-B2 2-furancarboxylic acid hydrazides and pharmaceutical compositions containing the same DAINIPPON PHARMACEUTICAL CO., LTD (JP) 2009-04-07 US disclosed
US-20050171196-A1 2-Furancarboxylic acid hydrazides and pharmaceutical compositions containing the same DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2005-08-04 US disclosed
EP-1489077-A1 2-FURANCARBOXYLIC ACID HYDRAZIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 2004-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050171196-A1 2-Furancarboxylic acid hydrazides and pharmaceutical compositions containing the same GLP1R, GCGR, GPR119 FFAR1 7/4885CD274 4366/4885PTGER4 1074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.