Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | CHKA | P35790 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL252099 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| Bromide SCHEMBL252100 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| SCHEMBL10557768 | 0.97 | ALDH1A1 (0.67) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| SCHEMBL8277 | 0.97 | — | — | |
| SCHEMBL7879117 | 0.97 | — | — | |
| SCHEMBL16187039 | 0.97 | — | — | |
| SCHEMBL21208167 | 0.97 | ALDH1A1 (0.67) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| Ethyne SCHEMBL11033667 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| SCHEMBL15546090 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 | |
| SCHEMBL4918905 | 0.93 | ALDH1A1 (0.62) | ALDH1A1TSHRHSD17B10ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431409-A | Bipyridine coordinated catalyst, preparation method, composite catalyst and application | 上海元革新材料科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-118098835-A | Electrolyte additive, electrolyte containing electrolyte additive and supercapacitor | 深圳市今朝时代股份有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-114634524-B | Preparation method and application of dimethylvinylchlorosilane | 江西贝特利新材料有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-114634524-A | Preparation method and application of dimethylvinylchlorosilane | 江西贝特利新材料有限公司 | 2022-06-17 | — | — | CN | claimed |
| CN-108623618-A | A kind of synthetic method of cefminox sodium | 广东立国制药有限公司 | 2018-10-09 | — | — | CN | claimed |
| CN-1705688-A | Multi-catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEM PATENTS INC (US) | 2005-12-07 | — | — | CN | claimed |
| EP-0461597-B1 | Method for preparing monohalogenosilanes | SHINETSU CHEMICAL CO (JP) | 1995-03-01 | — | — | EP | claimed |
| EP-0461597-A2 | Method for preparing monohalogenosilanes | Shin-Etsu Chemical Co., Ltd. (JP) | 1991-12-18 | — | — | EP | claimed |
| EP-0408277-A2 | Process for the preparation of aliphatic isocyanates | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1991-01-16 | — | — | EP | claimed |
| CN-119431409-A | Bipyridine coordinated catalyst, preparation method, composite catalyst and application | 上海元革新材料科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-118098835-A | Electrolyte additive, electrolyte containing electrolyte additive and supercapacitor | 深圳市今朝时代股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117295718-A | Method for preparing medetomidine and derivative thereof | 维科-兹多洛夫希沃特尼赫有限责任公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-114634524-B | Preparation method and application of dimethylvinylchlorosilane | 江西贝特利新材料有限公司 | 2023-12-26 | — | — | CN | disclosed |
| US-11660379-B2 | Durable antimicrobial layer for implantable medical devices | CARDIAC PACEMAKERS, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-4386085-A | ANTIGLUCOCORTICOIDS | ROUSSELL UCLAF (FR) | 1983-05-31 | — | — | US | disclosed |
| US-4331684-A | ARALKYL ESTERS OF AMINO ACIDS | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1982-05-25 | — | — | US | disclosed |
| US-4237311-A | ANTIDEPRESSANTS | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1980-12-02 | — | — | US | disclosed |
| US-4224453-A | ACID HALIDE IN NON-BASIC SOLVENT | CHEVRON RESEARCH COMPANY (US) | 1980-09-23 | — | — | US | disclosed |
| US-4165322-A | 3-(ALKYL-, ALKOXY-, HALO-, OR NITRO-SUBSTITUTED)PHENYLAMINO-GAMMA-BUTYROLACTONE OR BUTYROTHIOLACTONE | CHEVRON RESEARCH COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4013706-A | FROM A CYANAMIDE; ACID CATALYST | SUCRERIES DU SOISSONNAIS ET COMPAGNIE SUCRIERE (FR) | 1977-03-22 | — | — | US | disclosed |