Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.61 |
| ▸ | OGA | O60502 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210857 | 0.86 | P2RY12 (0.65) | P2RY12OGAHRH3KMT2ANPC1 | |
| SCHEMBL2820792 | 0.85 | P2RY12 (0.64) | P2RY12OGAHRH3KMT2ANPC1 | |
| SCHEMBL7529775 | 0.85 | P2RY12 (0.64) | P2RY12OGAHRH3KMT2ANPC1 | |
| SCHEMBL7469230 | 0.84 | P2RY12 (0.63) | P2RY12OGAHRH3KMT2ANPC1 | |
| SCHEMBL2428493 | 0.84 | P2RY12 (0.72) | P2RY12OGAHRH3KMT2ANPC1 | |
| SCHEMBL2427846 | 0.83 | P2RY12 (0.62) | P2RY12OGAHRH3HPGDSMN1; SMN2 | |
| SCHEMBL6584014 | 0.82 | KMT2A (0.75) | P2RY12OGAHRH3KMT2ANPC1 | |
| SCHEMBL386639 | 0.82 | P2RY12 (0.60) | P2RY12OGAHRH3KMT2ANPC1 | |
| SCHEMBL5089275 | 0.82 | PIK3CA (0.67) | P2RY12OGAHRH3KMT2ANPC1 | |
| SCHEMBL24421703 | 0.81 | KMT2A (0.51) | P2RY12OGAHRH3KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074120-A1 | TROPANE COMPOUNDS | Exelixis, Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2009055077-A1 | TROPANE COMPOUNDS | EXELIXIS, INC. (US) | 2009-04-30 | — | — | WO | disclosed |