Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | OGA | O60502 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428493 | 0.86 | P2RY12 (0.72) | KMT2ANPC1RAB9AMEN1P2RY12 | |
| SCHEMBL9210857 | 0.86 | P2RY12 (0.65) | KMT2ANPC1RAB9AMEN1P2RY12 | |
| SCHEMBL9211056 | 0.86 | KMT2A (1.00) | KMT2ANPC1RAB9AMEN1P2RY12 | |
| SCHEMBL2820792 | 0.85 | P2RY12 (0.64) | KMT2ANPC1RAB9AMEN1P2RY12 | |
| SCHEMBL9212828 | 0.85 | P2RY12 (0.64) | KMT2ANPC1RAB9AMEN1P2RY12 | |
| SCHEMBL5089275 | 0.85 | PIK3CA (0.67) | KMT2ANPC1RAB9AMEN1P2RY12 | |
| SCHEMBL7529775 | 0.85 | P2RY12 (0.64) | KMT2ANPC1RAB9AMEN1P2RY12 | |
| SCHEMBL7469230 | 0.84 | P2RY12 (0.63) | KMT2ANPC1RAB9AMEN1P2RY12 | |
| SCHEMBL2488088 | 0.83 | LMNA (0.54) | KMT2ANPC1RAB9AMEN1P2RY12 | |
| SCHEMBL6374746 | 0.82 | KDM4E (0.71) | KMT2ANPC1RAB9AMEN1P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177178-B1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | ABBOTT GMBH & CO KG (DE) | 2004-12-29 | — | — | EP | disclosed |
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |
| EP-1177178-A1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000068206-A1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |