Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979576 | 0.90 | GPR119 (0.49) | GPR119MMP8MMP13 | |
| SCHEMBL3986279 | 0.90 | GPR119 (0.51) | GPR119 | |
| SCHEMBL3982839 | 0.88 | GPR119 (0.58) | GPR119 | |
| SCHEMBL3979923 | 0.88 | GPR119 (0.56) | GPR119 | |
| SCHEMBL3979940 | 0.87 | GPR119 (0.48) | GPR119 | |
| SCHEMBL3980367 | 0.87 | GPR119 (0.53) | GPR119 | |
| SCHEMBL3982861 | 0.86 | GPR119 (0.53) | GPR119 | |
| SCHEMBL3982586 | 0.86 | GPR119 (0.50) | GPR119MMP8 | |
| SCHEMBL3980525 | 0.86 | GPR119 (0.48) | GPR119 | |
| SCHEMBL12569747 | 0.84 | GPR119 (0.66) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059516-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (publ) (SE) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008025798-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2008-03-06 | — | — | WO | disclosed |