SCHEMBL398002

SCHEMBL398002

CCCC(C)(C)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.56
KCNN4 O15554 1/20 0.43
MAPK1 P28482 1/20 0.42
CNR2 P34972 3/20 0.41
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.39
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575234 1.00 TAAR1 (0.56) TAAR1KCNN4MAPK1CNR2CYP2C19
SCHEMBL3368788 0.87 TAAR1 (0.64) TAAR1KCNN4MAPK1CYP2C19HIF1A
SCHEMBL598065 0.86 TAAR1 (0.52) TAAR1KCNN4MAPK1CNR2ESR1
Hydrogen Peroxide SCHEMBL2318659 0.84 TAAR1 (0.50) TAAR1CNR2ESR1ESR2
SCHEMBL9453768 0.84 CNR2 (0.54) TAAR1CNR2
SCHEMBL399240 0.84 CNR2 (0.54) TAAR1CNR2
SCHEMBL12786796 0.83 ALDH1A1 (0.42) TAAR1CNR2CYP2C19ALDH1A1ESR1
SCHEMBL10174953 0.83 ALDH1A1 (0.42) TAAR1CNR2CYP2C19ALDH1A1ESR1
SCHEMBL3083069 0.82 CNR2 (0.57) TAAR1CNR2
SCHEMBL6506230 0.82 CNR2 (0.57) TAAR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8569405-B2 Additive mixtures for styrenic polymers BASF SE (DE) 2013-10-29 US disclosed
EP-1249845-B1 Stabilized medium and high voltage cable insulation composition BASF SE (DE) 2012-07-11 EP disclosed
US-8217105-B2 Stabilized medium and high voltage insulation composition BASF SE (DE) 2012-07-10 US disclosed
EP-2074167-B1 STABILIZED MEDIUM AND HIGH VOLTAGE INSULATION COMPOSITION BASF SE (DE) 2012-04-18 EP disclosed
US-8101679-B2 Processing stabilizers for rubber compounding BASF SE (DE) 2012-01-24 US disclosed
EP-2238199-B1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (DE) 2011-08-31 EP disclosed
US-20110046278-A1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (US) 2011-02-24 US disclosed
EP-1848768-B1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2011-02-09 EP disclosed
US-20100130660-A1 PROCESSING STABILIZERS FOR RUBBER COMPOUNDING CIBA CORPORATION (US) 2010-05-27 US disclosed
US-20100036031-A1 STABILIZED MEDIUM AND HIGH VOLTAGE INSULATION COMPOSITION CIBA CORPORATION 2010-02-11 US disclosed
WO-2008046751-A2 STABILIZED MEDIUM AND HIGH VOLTAGE INSULATION COMPOSITION CIBA HOLDING INC. (CH) 2008-04-24 WO disclosed
US-20070203278-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 US disclosed
US-7056967-B2 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-06-06 US disclosed
US-20020198344-A1 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
EP-1249845-A2 Stabilized medium and high voltage cable insulation composition Ciba SC Holding AG (CH) 2002-10-16 EP disclosed
EP-0165209-B1 O,P-BIFUNCTIONALISED, O'-SUBSTITUTED PHENOLS CIBA-GEIGY AG (CH) 1989-07-19 EP disclosed
US-4759862-A O,p-bifunctionalized o'-substituted phenols CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
US-4741846-A STABILIZERS FOR POLYMERS OR LUBRICANTS CIBA-GEIGY CORPORATION (US) 1988-05-03 US disclosed
EP-0170624-B1 2,4,6-TRIFUNCTIONALIZED PHENOLS CIBA-GEIGY AG (CH) 1988-01-07 EP disclosed
EP-0170624-A2 2,4,6-Trifunctionalized phenols CIBA-GEIGY AG (CH) 1986-02-05 EP disclosed