SCHEMBL398003

SCHEMBL398003

CCC([C](C)C)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
HSD17B10 Q99714 1/20 0.52
ALDH1A1 P00352 3/20 0.47
POLB P06746 1/20 0.47
CRHBP P24387 2/20 0.46
CRHR2 Q13324 2/20 0.46
KCNQ2 O43526 2/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NOS3 P29474 1/20 0.46
NOS2 P35228 1/20 0.46
TSHR P16473 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
GAA P10253 2/20 0.45
KDM4A O75164 1/20 0.45
BCHE P06276 1/20 0.45
MAPT P10636 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TRPA1 O75762 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28081174 0.82 AOC3 (0.47) LMNAHSD17B10POLBKCNQ2NOS3
SCHEMBL13389213 0.82 LMNA (0.58) LMNAHSD17B10ALDH1A1POLBCRHBP
SCHEMBL1099218 0.82 LMNA (0.58) LMNAHSD17B10ALDH1A1POLBCRHBP
SCHEMBL13020177 0.82 LMNA (0.58) LMNAHSD17B10ALDH1A1POLBCRHBP
SCHEMBL2163831 0.82 LMNA (0.50) LMNAHSD17B10ALDH1A1POLBCRHBP
SCHEMBL4935067 0.81 LMNA (0.61) LMNAHSD17B10ALDH1A1POLBCRHBP
SCHEMBL10910457 0.80 LMNA (0.51) LMNAHSD17B10ALDH1A1POLBCRHBP
SCHEMBL13177046 0.79 LMNA (0.55) LMNAHSD17B10ALDH1A1POLBCRHBP
SCHEMBL10457243 0.79 LMNA (0.52) LMNAHSD17B10ALDH1A1POLBCRHBP
SCHEMBL1715 0.79 LMNA (0.59) LMNAHSD17B10ALDH1A1POLBCRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8569405-B2 Additive mixtures for styrenic polymers BASF SE (DE) 2013-10-29 US disclosed
EP-1249845-B1 Stabilized medium and high voltage cable insulation composition BASF SE (DE) 2012-07-11 EP disclosed
US-8217105-B2 Stabilized medium and high voltage insulation composition BASF SE (DE) 2012-07-10 US disclosed
EP-2074167-B1 STABILIZED MEDIUM AND HIGH VOLTAGE INSULATION COMPOSITION BASF SE (DE) 2012-04-18 EP disclosed
US-8101679-B2 Processing stabilizers for rubber compounding BASF SE (DE) 2012-01-24 US disclosed
EP-2238199-B1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (DE) 2011-08-31 EP disclosed
US-20110046278-A1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (US) 2011-02-24 US disclosed
EP-1848768-B1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2011-02-09 EP disclosed
US-20100130660-A1 PROCESSING STABILIZERS FOR RUBBER COMPOUNDING CIBA CORPORATION (US) 2010-05-27 US disclosed
US-20100036031-A1 STABILIZED MEDIUM AND HIGH VOLTAGE INSULATION COMPOSITION CIBA CORPORATION 2010-02-11 US disclosed
EP-1249845-A2 Stabilized medium and high voltage cable insulation composition Ciba SC Holding AG (CH) 2002-10-16 EP disclosed
US-5672723-A SELECTIVE HYDROLYSIS OR ALCOHOLYSIS OF A MIXTURE OF 1-ACYL-1-ALKYLHYDRAZINE AND 1-ACYL-2-ALKYLHYDRAZINE USING AN ACID CATALYST TO OBTAIN AN ACID OR ESTER AND THE STABLE 1-ACYL-2-ALKYLHYRAZINE NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1997-09-30 US disclosed
US-5596013-A INHIBITORS OF PHOSPHODIESTERASE TYPE IV AND PRODUCTION OF TUMOR NECROSIS FACTOR PFIZER INC (US) 1997-01-21 US disclosed
EP-0738270-A1 DIHYDRO PYRAZOLOPYRROLES PFIZER INC. (US) 1996-10-23 EP disclosed
US-5508300-A INHIBIT PHOSPHODIESTERASE AND PRODUCTION OF TUMOR NECROSIS FACTOR; TREATING INFLAMMATORY DISEASES PFIZER INC. (US) 1996-04-16 US disclosed
WO-1995019362-A1 DIHYDRO PYRAZOLOPYRROLES PFIZER INC. (US) 1995-07-20 WO disclosed
US-4759862-A O,p-bifunctionalized o'-substituted phenols CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
US-4741846-A STABILIZERS FOR POLYMERS OR LUBRICANTS CIBA-GEIGY CORPORATION (US) 1988-05-03 US disclosed
US-4559083-A CONTROLLING MONO-AND DICOTYLEDONOUS WEEDS USING A MIXTURE ALSO INCLUDING A DILUENT AND SURFACTANT ESZAKMAGYARORSZAGI VEGYIMUVEK (HU) 1985-12-17 US disclosed
US-4429345-A POLYSILOXANES AS DIELECTRICS DOW CORNING CORPORATION (US) 1984-01-31 US disclosed