Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973550 | 0.87 | — | — | |
| SCHEMBL24571251 | 0.77 | THRB (0.38) | THRBMEN1KMT2A | |
| SCHEMBL29348154 | 0.77 | THRB (0.38) | THRBMEN1KMT2A | |
| SCHEMBL23970304 | 0.77 | THRB (0.38) | THRBMEN1KMT2A | |
| SCHEMBL18713045 | 0.73 | — | — | |
| SCHEMBL17010885 | 0.73 | — | — | |
| SCHEMBL24850547 | 0.71 | THRB (0.32) | THRBMEN1KMT2A | |
| SCHEMBL29296272 | 0.69 | THRB (0.40) | THRBMEN1KMT2A | |
| SCHEMBL3973463 | 0.69 | — | — | |
| SCHEMBL24850022 | 0.68 | THRB (0.30) | THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074120-A1 | TROPANE COMPOUNDS | Exelixis, Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2009055077-A1 | TROPANE COMPOUNDS | EXELIXIS, INC. (US) | 2009-04-30 | — | — | WO | disclosed |