Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3990125 | 1.00 | APLNR (0.32) | APLNRALDH1A1MAPTMAPK1NPSR1 | |
| SCHEMBL3980462 | 0.72 | APLNR (0.35) | APLNR | |
| SCHEMBL3984663 | 0.72 | APLNR (0.35) | APLNR | |
| SCHEMBL3981825 | 0.72 | APLNR (0.35) | APLNR | |
| SCHEMBL3984126 | 0.69 | APLNR (0.31) | APLNR | |
| SCHEMBL10342515 | 0.69 | APLNR (0.36) | APLNR | |
| SCHEMBL11097199 | 0.69 | APLNR (0.36) | APLNR | |
| SCHEMBL3981778 | 0.67 | — | — | |
| SCHEMBL13240196 | 0.67 | — | — | |
| SCHEMBL3989824 | 0.67 | UGT2B7 (0.36) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562575-B1 | FUSED CYCLOALKYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF I.A. EPILEPSY | ABBOTT LAB (US) | 2009-05-20 | — | — | EP | claimed |