Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3981321 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL3982486 | 0.84 | SERPINE1 (0.45) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL3947584 | 0.84 | BRD4 (0.48) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL3982797 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL4762404 | 0.79 | BRD4 (0.42) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL3989040 | 0.78 | SERPINE1 (0.46) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL3946013 | 0.78 | BRD4 (0.50) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL3944386 | 0.78 | BRD4 (0.52) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL3986748 | 0.77 | SERPINE1 (0.47) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL3944372 | 0.77 | BRD4 (0.44) | ALDH1A1MEN1KMT2APOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888058-B1 | INHIBITORS OF SOLUBLE ADENYLATE CYCLASE | BAYER SCHERING PHARMA AG (DE) | 2009-05-20 | — | — | EP | claimed |