SCHEMBL398261

SCHEMBL398261

COCc1ccc(-c2c(N)ccc(-c3ccc(N)c(-c4ccc(COC)cc4)c3-c3ccc(COC)cc3)c2-c2ccc(COC)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
PTGS2 P35354 1/20 0.36
ALDH1A1 P00352 3/20 0.34
HSD17B10 Q99714 2/20 0.33
ERN1 O75460 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
AGXT P21549 5/20 0.32
IDO1 P14902 4/20 0.32
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
PDK2 Q15119 1/20 0.31
GHSR Q92847 1/20 0.31
APP P05067 1/20 0.31
CHEK1 O14757 1/20 0.31
GAA P10253 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18042136 0.79 BRD4 (0.40) L3MBTL1TDP1PTGS2ALDH1A1HSD17B10
SCHEMBL24560 0.76 TDP1 (0.46) TDP1PTGS2ALDH1A1HSD17B10CYP3A4
SCHEMBL198803 0.73 ERN1 (0.47) L3MBTL1TDP1PTGS2ERN1AGXT
SCHEMBL398262 0.73 MAOB (0.37) L3MBTL1TDP1PTGS2ALDH1A1CYP3A4
SCHEMBL353048 0.72 TDP1 (0.41) L3MBTL1TDP1PTGS2ALDH1A1HSD17B10
SCHEMBL7136095 0.72 CYP3A4 (0.50) L3MBTL1TDP1PTGS2ALDH1A1HSD17B10
SCHEMBL9330647 0.72 TDP1 (0.48) L3MBTL1TDP1ALDH1A1HSD17B10CYP3A4
SCHEMBL134443 0.71 IDO1 (0.46) PTGS2ERN1TSHRAGXTIDO1
SCHEMBL18334896 0.70 CYP19A1 (0.39) TDP1PTGS2ALDH1A1ERN1CYP3A4
SCHEMBL10706144 0.70 TAAR1 (0.38) TDP1ALDH1A1HSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2408572-A1 COMPOSITE STRUCTURED ORGANIC FILMS Xerox Corporation (US) 2012-01-25 EP disclosed
EP-2403670-A1 STRUCTURED ORGANIC FILMS Xerox Corporation (US) 2012-01-11 EP disclosed
EP-2403858-A1 STRUCTURED ORGANIC FILMS HAVING AN ADDED FUNCTIONALITY Xerox Corporation (US) 2012-01-11 EP disclosed
EP-2403655-A1 MIXED SOLVENT PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS Xerox Corporation (US) 2012-01-11 EP disclosed
EP-2403657-A1 PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS (SOFS) VIA A PRE-SOF Xerox Corporation (US) 2012-01-11 EP disclosed
EP-2403656-A1 ELECTRONIC DEVICES COMPRISING STRUCTURED ORGANIC FILMS Xerox Corporation (US) 2012-01-11 EP disclosed
WO-2010102038-A1 ELECTRONIC DEVICES COMPRISING STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-10 WO disclosed
WO-2010102018-A1 MIXED SOLVENT PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-10 WO disclosed
WO-2010102025-A1 STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-10 WO disclosed
WO-2010102043-A1 PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS (SOFS) VIA A PRE-SOF XEROX CORPORATION (US) 2010-09-10 WO disclosed
WO-2010102036-A1 STRUCTURED ORGANIC FILMS HAVING AN ADDED FUNCTIONALITY XEROX CORPORATION (US) 2010-09-10 WO disclosed
WO-2010102027-A1 COMPOSITE STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-10 WO disclosed