Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398261 | 0.79 | L3MBTL1 (0.39) | BRD4CREBBPL3MBTL1TDP1NPC1 | |
| SCHEMBL1243997 | 0.79 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1HSD17B10PTPRCADORA2A | |
| SCHEMBL3794694 | 0.77 | NPC1 (0.51) | TDP1ATMNPC1RAB9AALDH1A1 | |
| SCHEMBL28184960 | 0.76 | BRD4 (0.41) | BRD4CREBBPL3MBTL1TDP1RAB9A | |
| SCHEMBL4908052 | 0.75 | HSD11B1 (0.45) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL11909531 | 0.74 | ABL1 (0.45) | ALDH1A1MEN1KMT2AAPPHSD17B10 | |
| SCHEMBL4843094 | 0.74 | ADORA2A (0.50) | L3MBTL1TDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL138249 | 0.74 | ALDH1A1 (0.44) | L3MBTL1TDP1ALDH1A1MEN1MAPT | |
| SCHEMBL15407028 | 0.73 | AKR1B1 (0.38) | ALDH1A1KDM4EMEN1POLBMAPT | |
| SCHEMBL25810005 | 0.72 | MAOB (0.44) | BRD4CREBBPL3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10281831-B2 | Imaging members comprising capped structured organic film compositions | XEROX CORPORATION (US) | 2019-05-07 | — | — | US | claimed |
| US-10281831-B2 | Imaging members comprising capped structured organic film compositions | XEROX CORPORATION (US) | 2019-05-07 | — | — | US | disclosed |
| US-20160259256-A1 | IMAGING MEMBERS COMPRISING CAPPED STRUCTURED ORGANIC FILM COMPOSITIONS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2016-09-08 | — | — | US | disclosed |