Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2987852 | 0.83 | PTGIR (0.46) | PTGDR2LPAR1LPAR5PTGDRSTAT3 | |
| SCHEMBL2979645 | 0.79 | OPRM1 (0.42) | PTGDR2LPAR1LPAR5PTGDR | |
| SCHEMBL2979609 | 0.76 | PTGDR2 (0.61) | PTGDR2PTGDRCYP2D6 | |
| SCHEMBL2991405 | 0.75 | PTGDR2 (0.61) | PTGDR2PTGDR | |
| SCHEMBL2982722 | 0.75 | PTGDR2 (0.51) | PTGDR2PTGDR | |
| SCHEMBL2986242 | 0.74 | PTGDR2 (0.46) | PTGDR2PTGDR | |
| SCHEMBL2979643 | 0.73 | PTGDR2 (0.62) | PTGDR2PTGDRKMT2A | |
| SCHEMBL2987848 | 0.73 | PTGDR2 (0.49) | PTGDR2PTGDR | |
| SCHEMBL2982720 | 0.70 | PTGDR2 (0.60) | PTGDR2PTGDR | |
| SCHEMBL12761132 | 0.70 | KDM4E (0.64) | PTGDR2PTGDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057115-A1 | 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008024746-A1 | 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES | ARRAY BIOPHARMA, INC. (US) | 2008-02-28 | — | — | WO | disclosed |