Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28771877 | 0.94 | KDM4E (0.38) | KDM4EALDH1A1RXFP1GAAHPGD | |
| Sulfuric Acid SCHEMBL21331906 | 0.91 | KDM4E (0.33) | KDM4EALDH1A1RXFP1HTT | |
| SCHEMBL18879397 | 0.89 | KDM4E (0.32) | KDM4EALDH1A1RXFP1 | |
| Sulfuric Acid SCHEMBL26128306 | 0.88 | KDM4E (0.31) | KDM4EALDH1A1RXFP1 | |
| SCHEMBL3945856 | 0.85 | KDM4E (0.34) | KDM4EALDH1A1RXFP1 | |
| Trifluoromethanesulfonic Acid SCHEMBL2396296 | 0.85 | KCNH2 (0.42) | KDM4EALDH1A1RXFP1 | |
| SCHEMBL18879396 | 0.85 | ACHE (0.32) | KDM4EALDH1A1RXFP1HPGDRECQL | |
| SCHEMBL329178 | 0.84 | HTT (0.35) | KDM4EHTTMAPTTHRB | |
| SCHEMBL17713599 | 0.83 | RECQL (0.35) | HPGDRECQL | |
| Phosphoric Acid SCHEMBL14164747 | 0.83 | GGPS1 (0.31) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238993-B2 | Process for the preparation of polyisocyanates by reaction of carboxylic acids with isocyanates, products prepared by this process and their use in polyurethanes | BAYER MATERIALSCIENCE AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-7071353-B2 | Polyisocyanates containing acylurea groups, a process for their production and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2006-07-04 | — | — | US | disclosed |
| EP-1238993-B1 | Process for the preparation of polyisocyanates by reaction of carboxylic acids with isocyanates, products prepared by this process and their use in polyurethanes | BAYER MATERIALSCIENCE AG (DE) | 2005-11-23 | — | — | EP | disclosed |
| EP-1238993-A1 | Process for the preparation of polyisocyanates by reaction of carboxylic acids with isocyanates, products prepared by this process and their use in polyurethanes | BAYER AG (DE) | 2002-09-11 | — | — | EP | disclosed |
| US-20020123596-A1 | Polyisocyanates containing acylurea groups, a process for their production and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-05 | — | — | US | disclosed |