Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCK1 | P35558 | 20/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983384 | 0.94 | PCK1 (0.88) | PCK1 | |
| SCHEMBL3978767 | 0.93 | PCK1 (1.00) | PCK1 | |
| SCHEMBL3981765 | 0.90 | PCK1 (0.95) | PCK1 | |
| SCHEMBL3980864 | 0.90 | PCK1 (0.81) | PCK1 | |
| SCHEMBL3978817 | 0.90 | PCK1 (0.81) | PCK1 | |
| SCHEMBL6443781 | 0.90 | PCK1 (0.81) | PCK1 | |
| SCHEMBL3977016 | 0.90 | PCK1 (0.83) | PCK1 | |
| SCHEMBL3979611 | 0.89 | PCK1 (0.70) | PCK1 | |
| SCHEMBL4614586 | 0.89 | PCK1 (0.82) | PCK1 | |
| SCHEMBL3980735 | 0.87 | PCK1 (0.80) | PCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515972-B1 | AMIDE SUBSTITUTED XANTHINE DERIVATIVES WITH GLUCONEOGENESIS MODULATING ACTIVITY | HOFFMANN LA ROCHE (CH) | 2009-05-13 | — | — | EP | claimed |
| EP-1599477-B1 | SULFONAMIDE SUBSTITUTED XANTHINE DERIVATIVES FOR USE AS PEPCK INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-01-30 | — | — | EP | claimed |