SCHEMBL3983556

SCHEMBL3983556

O=[C]C1C(=O)C=Cc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.41
HTR2A P28223 2/20 0.39
KDM4E B2RXH2 4/20 0.36
HSD17B10 Q99714 3/20 0.36
TP53 P04637 2/20 0.36
CYP3A4 P08684 2/20 0.36
LMNA P02545 2/20 0.36
BRD4 O60885 1/20 0.36
CCL2 P13500 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
DRD2 P14416 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
NFKB1 P19838 1/20 0.36
CHRM3 P20309 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8910040 0.87 HTR2A (0.45) CYP2D6HTR2AKDM4EHSD17B10TP53
SCHEMBL7913606 0.82 PIM1 (0.44) CYP2D6HTR2AKDM4EHSD17B10TP53
SCHEMBL2198383 0.78 HTR2A (0.38) CYP2D6HTR2AKDM4EHSD17B10TP53
SCHEMBL3083806 0.78
SCHEMBL7334568 0.75 HTR2A (0.47) CYP2D6HTR2AKDM4EHSD17B10TP53
SCHEMBL8522211 0.74 CYP2D6 (0.50) CYP2D6HTR2AKDM4EHSD17B10TP53
SCHEMBL28710347 0.73 HTR2A (0.45) CYP2D6HTR2AKDM4EHSD17B10TP53
SCHEMBL29450602 0.73 HTR2A (0.45) CYP2D6HTR2AKDM4EHSD17B10TP53
SCHEMBL12573963 0.71 BRD4 (0.55) CYP2D6HTR2AKDM4EHSD17B10TP53
SCHEMBL7074288 0.71 CYP2D6 (0.51) CYP2D6HTR2AKDM4EHSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61276819-A None JP disclosed
EP-2476729-B1 METHOD FOR PRODUCING STEREO COMPLEX CRYSTALS OF POLYLACTIC ACID, POLYLACTIC ACID, AND MOLDED BODY, SYNTHETIC FIBER, POROUS BODY AND ION CONDUCTOR COMPRISING SAME UNIV GUNMA NAT UNIV CORP (JP) 2016-08-17 EP disclosed
US-9045601-B2 Method for producing stereo complex crystals of polylactic acid, polylactic acid, and molded body, synthetic fiber, porous body and ion conductor comprising same NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) 2015-06-02 US disclosed
US-8304490-B2 Polylactic acid and manufacturing process thereof TEIJIN LIMITED (JP) 2012-11-06 US disclosed
US-20120238652-A1 METHOD FOR PRODUCING STEREO COMPLEX CRYSTALS OF POLYLACTIC ACID, POLYLACTIC ACID, AND MOLDED BODY, SYNTHETIC FIBER, POROUS BODY AND ION CONDUCTOR COMPRISING SAME NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) 2012-09-20 US disclosed
EP-2476729-A1 METHOD FOR PRODUCING STEREO COMPLEX CRYSTALS OF POLYLACTIC ACID, POLYLACTIC ACID, AND MOLDED BODY, SYNTHETIC FIBER, POROUS BODY AND ION CONDUCTOR COMPRISING SAME National University Corporation Gunma University (JP) 2012-07-18 EP disclosed
US-20090270533-A1 HEAT-CURABLE POWDER COATING COMPOSITION BASF COATINGS JAPAN LTD. (JP) 2009-10-29 US disclosed
EP-2021417-A2 HEAT-CURABLE POWDER COATING COMPOSITION BASF Coatings Japan Ltd. (JP) 2009-02-11 EP disclosed
US-20080039579-A1 Polyactic Acid and Manufacturing Process Thereof TEIJIN LIMITED (JP) 2008-02-14 US disclosed
WO-2007138399-A2 HEAT-CURABLE POWDER COATING COMPOSITION BASF COATINGS JAPAN LTD. (DE) 2007-12-06 WO disclosed
EP-0074700-A1 Poly(ester amide) derived from 6-hydroxy-2-naphthoic acid, another aromatic hydroxy acid, dicarboxylic acid and an aromatic monomer capable of forming an amide link CELANESE CORPORATION (US) 1983-03-23 EP disclosed
EP-0067032-A1 Poly(ester-amide) capable of forming an anisotropic melt phase derived from p-hydroxybenzoic acid, 2,6-dihydroxynaphthalene, carbocyclic dicarboxylic acid, aromatic monomer capable of forming an amide linkage and, optinally, additional aromatic diol CELANESE CORPORATION (US) 1982-12-15 EP disclosed
EP-0066359-A1 Poly(ester amide) derived from dihydroxy anthraquinone, hydroxybenzoic acid, dicarboxylic acid and aromatic monomer capable of forming an amide linkage CELANESE CORPORATION (US) 1982-12-08 EP disclosed
EP-0063881-A1 Poly(ester-amide) derived from p-hydroxybenzoic acid, 2,6-naphthalene-dicarboxylic acid and aromatic monomer capable of forming an amide linkage CELANESE CORPORATION (US) 1982-11-03 EP disclosed
EP-0063880-A1 Poly(esteramide) derived from 6-hydroxy-2-naphthoic acid CELANESE CORPORATION (US) 1982-11-03 EP disclosed
US-4355132-A Anisotropic melt phase forming poly(ester-amide) derived from p-hydroxybenzoic acid, 2,6-naphthalenedicarboxylic acid, aromatic monomer capable of forming an amide linkage, and, optionally, hydroquinone and additional carbocyclic dicarboxylic acid CELANESE CORPORATION (US) 1982-10-19 US disclosed
US-4351917-A MOLDING MATERIALS CELANESE CORPORATION (US) 1982-09-28 US disclosed
US-4351918-A Poly(ester-amide) capable of forming an anisotropic melt phase derived from 6-hydroxy-2-naphthoic acid, other aromatic hydroxyacid, carbocyclic dicarboxylic acid, and aromatic monomer capable of forming an amide linkage CELANESE CORPORATION (US) 1982-09-28 US disclosed
US-4341688-A Poly(ester-amide) capable of forming an anisotropic melt phase derived from dihydroxyanthraquinone, hydroxybenzoic acid, dicarboxylic acid, and aromatic monomer capable of forming an amide linkage CELANESE CORPORATION (US) 1982-07-27 US disclosed
US-4339375-A Poly(ester-amide) capable of forming an anisotropic melt phase derived from p-hydroxybenzoic acid, 2,6-dihydroxynaphthalene, carbocyclic dicarboxylic acid, aromatic monomer capable of forming an amide linkage, and, optionally, additional aromatic diol CELANESE CORPORATION (US) 1982-07-13 US disclosed